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Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH.
Zhu N, Swietlik EM, Welch CL, Pauciulo MW, Hagen JJ, Zhou X, Guo Y, Karten J, Pandya D, Tilly T, Lutz KA, Martin JM, Treacy CM, Rosenzweig EB, Krishnan U, Coleman AW, Gonzaga-Jauregui C, Lawrie A, Trembath RC, Wilkins MR; Regeneron Genetics Center; PAH Biobank Enrolling Centers’ Investigators; NIHR BioResource for Translational Research - Rare Diseases; National Cohort Study of Idiopathic and Heritable PAH; Morrell NW, Shen Y, Gräf S, Nichols WC, Chung WK. Zhu N, et al. Among authors: wilkins mr. Genome Med. 2021 May 10;13(1):80. doi: 10.1186/s13073-021-00891-1. Genome Med. 2021. PMID: 33971972 Free PMC article.
Genetic association of the serotonin transporter in pulmonary arterial hypertension.
Machado RD, Koehler R, Glissmeyer E, Veal C, Suntharalingam J, Kim M, Carlquist J, Town M, Elliott CG, Hoeper M, Fijalkowska A, Kurzyna M, Thomson JR, Gibbs SR, Wilkins MR, Seeger W, Morrell NW, Gruenig E, Trembath RC, Janssen B. Machado RD, et al. Among authors: wilkins mr. Am J Respir Crit Care Med. 2006 Apr 1;173(7):793-7. doi: 10.1164/rccm.200509-1365OC. Epub 2006 Jan 6. Am J Respir Crit Care Med. 2006. PMID: 16399993
Emerging therapies for pulmonary arterial hypertension.
Ali O, Wharton J, Gibbs JS, Howard L, Wilkins MR. Ali O, et al. Among authors: wilkins mr. Expert Opin Investig Drugs. 2007 Jun;16(6):803-18. doi: 10.1517/13543784.16.6.803. Expert Opin Investig Drugs. 2007. PMID: 17501693 Review.
Therapeutic targets in pulmonary arterial hypertension.
Rhodes CJ, Davidson A, Gibbs JS, Wharton J, Wilkins MR. Rhodes CJ, et al. Among authors: wilkins mr. Pharmacol Ther. 2009 Jan;121(1):69-88. doi: 10.1016/j.pharmthera.2008.10.002. Epub 2008 Oct 28. Pharmacol Ther. 2009. PMID: 19010350 Review.
568 results