Clarkson MW - Search Results

1

NMR Based SARS-CoV-2 Antibody Screening.

Schoenle MV, Li Y, Yuan M, Clarkson MW, Wilson IA, Peti W, Page R. Schoenle MV, et al. Among authors: clarkson mw. J Am Chem Soc. 2021 Jun 2;143(21):7930-7934. doi: 10.1021/jacs.1c03945. Epub 2021 May 21. J Am Chem Soc. 2021. PMID: 34018723

2

Ligand binding reduces conformational flexibility in the active site of tyrosine phosphatase related to biofilm formation A (TpbA) from Pseudomonasaeruginosa.

Koveal D, Clarkson MW, Wood TK, Page R, Peti W. Koveal D, et al. Among authors: clarkson mw. J Mol Biol. 2013 Jun 26;425(12):2219-31. doi: 10.1016/j.jmb.2013.03.023. Epub 2013 Mar 21. J Mol Biol. 2013. PMID: 23524133 Free PMC article.

3

Dynamic activation and regulation of the mitogen-activated protein kinase p38.

Kumar GS, Clarkson MW, Kunze MBA, Granata D, Wand AJ, Lindorff-Larsen K, Page R, Peti W. Kumar GS, et al. Among authors: clarkson mw. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4655-4660. doi: 10.1073/pnas.1721441115. Epub 2018 Apr 16. Proc Natl Acad Sci U S A. 2018. PMID: 29666261 Free PMC article.

4

Cooperative dynamics across distinct structural elements regulate PTP1B activity.

Torgeson KR, Clarkson MW, Kumar GS, Page R, Peti W. Torgeson KR, et al. Among authors: clarkson mw. J Biol Chem. 2020 Oct 2;295(40):13829-13837. doi: 10.1074/jbc.RA120.014652. Epub 2020 Jul 31. J Biol Chem. 2020. PMID: 32737198 Free PMC article.

5

Conserved conformational dynamics determine enzyme activity.

Torgeson KR, Clarkson MW, Granata D, Lindorff-Larsen K, Page R, Peti W. Torgeson KR, et al. Among authors: clarkson mw. Sci Adv. 2022 Aug 5;8(31):eabo5546. doi: 10.1126/sciadv.abo5546. Epub 2022 Aug 3. Sci Adv. 2022. PMID: 35921420 Free PMC article.

6

Retinoic Acid Binding Leads to CRABP2 Rigidification and Dimerization.

Lixa C, Clarkson MW, Iqbal A, Moon TM, Almeida FCL, Peti W, Pinheiro AS. Lixa C, et al. Among authors: clarkson mw. Biochemistry. 2019 Oct 15;58(41):4183-4194. doi: 10.1021/acs.biochem.9b00672. Epub 2019 Oct 7. Biochemistry. 2019. PMID: 31566355

7

Dynamic coupling and allosteric behavior in a nonallosteric protein.

Clarkson MW, Gilmore SA, Edgell MH, Lee AL. Clarkson MW, et al. Biochemistry. 2006 Jun 27;45(25):7693-9. doi: 10.1021/bi060652l. Biochemistry. 2006. PMID: 16784220 Free PMC article.

8

Mesodynamics in the SARS nucleocapsid measured by NMR field cycling.

Clarkson MW, Lei M, Eisenmesser EZ, Labeikovsky W, Redfield A, Kern D. Clarkson MW, et al. J Biomol NMR. 2009 Sep;45(1-2):217-25. doi: 10.1007/s10858-009-9347-6. Epub 2009 Jul 30. J Biomol NMR. 2009. PMID: 19641854 Free PMC article.

9

Structural Dynamics of the Activation of Elongation Factor 2 Kinase by Ca²⁺-Calmodulin.

Will N, Lee K, Hajredini F, Giles DH, Abzalimov RR, Clarkson M, Dalby KN, Ghose R. Will N, et al. J Mol Biol. 2018 Aug 17;430(17):2802-2821. doi: 10.1016/j.jmb.2018.05.033. Epub 2018 May 22. J Mol Biol. 2018. PMID: 29800565 Free PMC article.

10

Rescue of conformational dynamics in enzyme catalysis by directed evolution.

Otten R, Liu L, Kenner LR, Clarkson MW, Mavor D, Tawfik DS, Kern D, Fraser JS. Otten R, et al. Among authors: clarkson mw. Nat Commun. 2018 Apr 3;9(1):1314. doi: 10.1038/s41467-018-03562-9. Nat Commun. 2018. PMID: 29615624 Free PMC article.

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