Kabadi AM - Search Results

1

Epigenome editing of the CFTR-locus for treatment of cystic fibrosis.

Kabadi AM, Machlin L, Dalal N, Lee RE, McDowell I, Shah NN, Drowley L, Randell SH, Reddy TE. Kabadi AM, et al. J Cyst Fibros. 2022 Jan;21(1):164-171. doi: 10.1016/j.jcf.2021.04.008. Epub 2021 May 25. J Cyst Fibros. 2022. PMID: 34049825 Free PMC article.

2

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.

Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA. Thakore PI, et al. Among authors: kabadi am. Nat Methods. 2015 Dec;12(12):1143-9. doi: 10.1038/nmeth.3630. Epub 2015 Oct 26. Nat Methods. 2015. PMID: 26501517 Free PMC article.

3

Applications of Functional Genomics for Drug Discovery.

Kabadi A, McDonnell E, Frank CL, Drowley L. Kabadi A, et al. SLAS Discov. 2020 Sep;25(8):823-842. doi: 10.1177/2472555220902092. Epub 2020 Feb 6. SLAS Discov. 2020. PMID: 32026742 Free article. Review.

4

Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.

Ousterout DG, Kabadi AM, Thakore PI, Majoros WH, Reddy TE, Gersbach CA. Ousterout DG, et al. Among authors: kabadi am. Nat Commun. 2015 Feb 18;6:6244. doi: 10.1038/ncomms7244. Nat Commun. 2015. PMID: 25692716 Free PMC article.

5

RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA. Perez-Pinera P, et al. Among authors: kabadi am. Nat Methods. 2013 Oct;10(10):973-6. doi: 10.1038/nmeth.2600. Epub 2013 Jul 25. Nat Methods. 2013. PMID: 23892895 Free PMC article.

6

Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.

Ousterout DG, Kabadi AM, Thakore PI, Perez-Pinera P, Brown MT, Majoros WH, Reddy TE, Gersbach CA. Ousterout DG, et al. Among authors: kabadi am. Mol Ther. 2015 Mar;23(3):523-32. doi: 10.1038/mt.2014.234. Epub 2014 Dec 10. Mol Ther. 2015. PMID: 25492562 Free PMC article.

7

Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain.

Kabadi AM, Thakore PI, Vockley CM, Ousterout DG, Gibson TM, Guilak F, Reddy TE, Gersbach CA. Kabadi AM, et al. ACS Synth Biol. 2015 Jun 19;4(6):689-99. doi: 10.1021/sb500322u. Epub 2014 Dec 31. ACS Synth Biol. 2015. PMID: 25494287 Free PMC article.

8

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector.

Kabadi AM, Ousterout DG, Hilton IB, Gersbach CA. Kabadi AM, et al. Nucleic Acids Res. 2014 Oct 29;42(19):e147. doi: 10.1093/nar/gku749. Epub 2014 Aug 13. Nucleic Acids Res. 2014. PMID: 25122746 Free PMC article.

9

Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

Ousterout DG, Perez-Pinera P, Thakore PI, Kabadi AM, Brown MT, Qin X, Fedrigo O, Mouly V, Tremblay JP, Gersbach CA. Ousterout DG, et al. Among authors: kabadi am. Mol Ther. 2013 Sep;21(9):1718-26. doi: 10.1038/mt.2013.111. Epub 2013 Jun 4. Mol Ther. 2013. PMID: 23732986 Free PMC article.

10

Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression.

Kabadi AM, Gersbach CA. Kabadi AM, et al. Methods. 2014 Sep;69(2):188-97. doi: 10.1016/j.ymeth.2014.06.014. Epub 2014 Jul 8. Methods. 2014. PMID: 25010559 Free PMC article.

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