Zager M - Search Results

1

Integrated analysis of multimodal single-cell data.

Hao Y, Hao S, Andersen-Nissen E, Mauck WM 3rd, Zheng S, Butler A, Lee MJ, Wilk AJ, Darby C, Zager M, Hoffman P, Stoeckius M, Papalexi E, Mimitou EP, Jain J, Srivastava A, Stuart T, Fleming LM, Yeung B, Rogers AJ, McElrath JM, Blish CA, Gottardo R, Smibert P, Satija R. Hao Y, et al. Among authors: zager m. Cell. 2021 Jun 24;184(13):3573-3587.e29. doi: 10.1016/j.cell.2021.04.048. Epub 2021 May 31. Cell. 2021. PMID: 34062119 Free PMC article.

2

The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models.

Palsson S, Hickling TP, Bradshaw-Pierce EL, Zager M, Jooss K, O'Brien PJ, Spilker ME, Palsson BO, Vicini P. Palsson S, et al. Among authors: zager m. BMC Syst Biol. 2013 Sep 28;7:95. doi: 10.1186/1752-0509-7-95. BMC Syst Biol. 2013. PMID: 24074340 Free PMC article.

3

GPS for QSP: A Summary of the ACoP6 Symposium on Quantitative Systems Pharmacology and a Stage for Near-Term Efforts in the Field.

Musante CJ, Abernethy DR, Allerheiligen SR, Lauffenburger DA, Zager MG. Musante CJ, et al. Among authors: zager mg. CPT Pharmacometrics Syst Pharmacol. 2016 Sep;5(9):449-51. doi: 10.1002/psp4.12109. Epub 2016 Sep 17. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27639191 Free PMC article.

4

A multiscale, mechanism-driven, dynamic model for the effects of 5α-reductase inhibition on prostate maintenance.

Zager MG, Barton HA. Zager MG, et al. PLoS One. 2012;7(9):e44359. doi: 10.1371/journal.pone.0044359. Epub 2012 Sep 6. PLoS One. 2012. PMID: 22970204 Free PMC article.

5

Preclinical PK/PD modeling and human efficacious dose projection for a glucokinase activator in the treatment of diabetes.

Zager MG, Kozminski K, Pascual B, Ogilvie KM, Sun S. Zager MG, et al. J Pharmacokinet Pharmacodyn. 2014 Apr;41(2):127-39. doi: 10.1007/s10928-014-9351-7. Epub 2014 Feb 28. J Pharmacokinet Pharmacodyn. 2014. PMID: 24578187

6

Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth.

Murray BW, Guo C, Piraino J, Westwick JK, Zhang C, Lamerdin J, Dagostino E, Knighton D, Loi CM, Zager M, Kraynov E, Popoff I, Christensen JG, Martinez R, Kephart SE, Marakovits J, Karlicek S, Bergqvist S, Smeal T. Murray BW, et al. Among authors: zager m. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9446-51. doi: 10.1073/pnas.0911863107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439741 Free PMC article.

7

Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.

Potter LK, Zager MG, Barton HA. Potter LK, et al. Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E952-64. doi: 10.1152/ajpendo.00545.2005. Epub 2006 Jun 6. Am J Physiol Endocrinol Metab. 2006. PMID: 16757547 Free article.

8

Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer.

Kung PP, Martinez R, Zhu Z, Zager M, Blasina A, Rymer I, Hallin J, Xu M, Carroll C, Chionis J, Wells P, Kozminski K, Fan J, Guicherit O, Huang B, Cui M, Liu C, Huang Z, Sistla A, Yang J, Murray BW. Kung PP, et al. Among authors: zager m. Mol Cancer Ther. 2014 Aug;13(8):2104-15. doi: 10.1158/1535-7163.MCT-14-0083-T. Epub 2014 Jun 13. Mol Cancer Ther. 2014. PMID: 24928852

9

A delayed nonlinear PBPK model for genistein dosimetry in rats.

Zager MG, Schlosser PM, Tran HT. Zager MG, et al. Bull Math Biol. 2007 Jan;69(1):93-117. doi: 10.1007/s11538-006-9068-x. Bull Math Biol. 2007. PMID: 17024552

10

Model-informed drug development of voxelotor in sickle cell disease: Population pharmacokinetics in whole blood and plasma.

Savic RM, Green ML, Jorga K, Zager M, Washington CB. Savic RM, et al. Among authors: zager m. CPT Pharmacometrics Syst Pharmacol. 2022 Jun;11(6):687-697. doi: 10.1002/psp4.12731. Epub 2022 Apr 21. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35447014 Free PMC article.

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