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Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.
van Schouwenburg PA, van de Stadt LA, de Jong RN, van Buren EE, Kruithof S, de Groot E, Hart M, van Ham SM, Rispens T, Aarden L, Wolbink GJ, Wouters D. van Schouwenburg PA, et al. Among authors: rispens t. Ann Rheum Dis. 2013 Jan;72(1):104-9. doi: 10.1136/annrheumdis-2012-201445. Epub 2012 Jul 3. Ann Rheum Dis. 2013. PMID: 22759910
Increased IgG4 responses to multiple food and animal antigens indicate a polyclonal expansion and differentiation of pre-existing B cells in IgG4-related disease.
Culver EL, Vermeulen E, Makuch M, van Leeuwen A, Sadler R, Cargill T, Klenerman P, Aalberse RC, van Ham SM, Barnes E, Rispens T. Culver EL, et al. Among authors: rispens t. Ann Rheum Dis. 2015 May;74(5):944-7. doi: 10.1136/annrheumdis-2014-206405. Epub 2015 Feb 2. Ann Rheum Dis. 2015. PMID: 25646372 Free PMC article.
Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region.
van de Bovenkamp FS, Derksen NIL, Ooijevaar-de Heer P, van Schie KA, Kruithof S, Berkowska MA, van der Schoot CE, IJspeert H, van der Burg M, Gils A, Hafkenscheid L, Toes REM, Rombouts Y, Plomp R, Wuhrer M, van Ham SM, Vidarsson G, Rispens T. van de Bovenkamp FS, et al. Among authors: rispens t. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1901-1906. doi: 10.1073/pnas.1711720115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432186 Free PMC article.
291 results