Holzbaur ELF - Search Results

1

ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy.

Harding O, Evans CS, Ye J, Cheung J, Maniatis T, Holzbaur ELF. Harding O, et al. Among authors: holzbaur elf. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2025053118. doi: 10.1073/pnas.2025053118. Proc Natl Acad Sci U S A. 2021. PMID: 34099552 Free PMC article.

2

Microtubule plus-end tracking by CLIP-170 requires EB1.

Dixit R, Barnett B, Lazarus JE, Tokito M, Goldman YE, Holzbaur EL. Dixit R, et al. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):492-7. doi: 10.1073/pnas.0807614106. Epub 2009 Jan 6. Proc Natl Acad Sci U S A. 2009. PMID: 19126680 Free PMC article.

3

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.

Wong YC, Holzbaur EL. Wong YC, et al. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4439-48. doi: 10.1073/pnas.1405752111. Epub 2014 Oct 7. Proc Natl Acad Sci U S A. 2014. PMID: 25294927 Free PMC article.

4

Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria.

Wong YC, Holzbaur EL. Wong YC, et al. Autophagy. 2015;11(2):422-4. doi: 10.1080/15548627.2015.1009792. Autophagy. 2015. PMID: 25801386 Free PMC article.

5

Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy.

Moore AS, Holzbaur EL. Moore AS, et al. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3349-58. doi: 10.1073/pnas.1523810113. Epub 2016 May 31. Proc Natl Acad Sci U S A. 2016. PMID: 27247382 Free PMC article.

6

Spatiotemporal dynamics of autophagy receptors in selective mitophagy.

Moore AS, Holzbaur EL. Moore AS, et al. Autophagy. 2016 Oct 2;12(10):1956-1957. doi: 10.1080/15548627.2016.1212788. Epub 2016 Aug 2. Autophagy. 2016. PMID: 27484150 Free PMC article.

7

Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.

Gopal PP, Nirschl JJ, Klinman E, Holzbaur EL. Gopal PP, et al. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2466-E2475. doi: 10.1073/pnas.1614462114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265061 Free PMC article.

8

Autophagy and mitophagy in ALS.

Evans CS, Holzbaur ELF. Evans CS, et al. Among authors: holzbaur elf. Neurobiol Dis. 2019 Feb;122:35-40. doi: 10.1016/j.nbd.2018.07.005. Epub 2018 Jul 5. Neurobiol Dis. 2019. PMID: 29981842 Free PMC article. Review.

9

Imaging the Dynamics of Mitophagy in Live Cells.

Moore AS, Holzbaur ELF. Moore AS, et al. Among authors: holzbaur elf. Methods Mol Biol. 2019;1880:601-610. doi: 10.1007/978-1-4939-8873-0_39. Methods Mol Biol. 2019. PMID: 30610725

10

Quality Control in Neurons: Mitophagy and Other Selective Autophagy Mechanisms.

Evans CS, Holzbaur ELF. Evans CS, et al. Among authors: holzbaur elf. J Mol Biol. 2020 Jan 3;432(1):240-260. doi: 10.1016/j.jmb.2019.06.031. Epub 2019 Jul 8. J Mol Biol. 2020. PMID: 31295455 Free PMC article. Review.

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