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Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission.
Chang XL, Webb GM, Wu HL, Greene JM, Abdulhaqq S, Bateman KB, Reed JS, Pessoa C, Weber WC, Maier N, Chew GM, Gilbride RM, Gao L, Agnor R, Giobbi T, Torgerson J, Siess D, Burnett N, Fischer M, Shiel O, Moats C, Patterson B, Dhody K, Kelly S, Pourhassan N, Magnani DM, Smedley J, Bimber BN, Haigwood NL, Hansen SG, Brown TR, Ndhlovu LC, Sacha JB. Chang XL, et al. Among authors: haigwood nl. Nat Commun. 2021 Jun 7;12(1):3343. doi: 10.1038/s41467-021-23697-6. Nat Commun. 2021. PMID: 34099693 Free PMC article.
Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques.
Jaworski JP, Kobie J, Brower Z, Malherbe DC, Landucci G, Sutton WF, Guo B, Reed JS, Leon EJ, Engelmann F, Zheng B, Legasse A, Park B, Dickerson M, Lewis AD, Colgin LM, Axthelm M, Messaoudi I, Sacha JB, Burton DR, Forthal DN, Hessell AJ, Haigwood NL. Jaworski JP, et al. Among authors: haigwood nl. J Virol. 2013 Oct;87(19):10447-59. doi: 10.1128/JVI.00049-13. Epub 2013 Jul 24. J Virol. 2013. PMID: 23885083 Free PMC article.
HIV: tied down by its own receptor.
Haigwood NL. Haigwood NL. Nature. 2015 Mar 5;519(7541):36-7. doi: 10.1038/nature14205. Epub 2015 Feb 18. Nature. 2015. PMID: 25707798 No abstract available.
Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens.
Hessell AJ, Malherbe DC, Pissani F, McBurney S, Krebs SJ, Gomes M, Pandey S, Sutton WF, Burwitz BJ, Gray M, Robins H, Park BS, Sacha JB, LaBranche CC, Fuller DH, Montefiori DC, Stamatatos L, Sather DN, Haigwood NL. Hessell AJ, et al. Among authors: haigwood nl. J Immunol. 2016 Apr 1;196(7):3064-78. doi: 10.4049/jimmunol.1500527. Epub 2016 Mar 4. J Immunol. 2016. PMID: 26944928 Free PMC article.
Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques.
Hessell AJ, Jaworski JP, Epson E, Matsuda K, Pandey S, Kahl C, Reed J, Sutton WF, Hammond KB, Cheever TA, Barnette PT, Legasse AW, Planer S, Stanton JJ, Pegu A, Chen X, Wang K, Siess D, Burke D, Park BS, Axthelm MK, Lewis A, Hirsch VM, Graham BS, Mascola JR, Sacha JB, Haigwood NL. Hessell AJ, et al. Among authors: haigwood nl. Nat Med. 2016 Apr;22(4):362-8. doi: 10.1038/nm.4063. Epub 2016 Mar 21. Nat Med. 2016. PMID: 26998834 Free PMC article.
Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge.
Malherbe DC, Mendy J, Vang L, Barnette PT, Reed J, Lakhashe SK, Owuor J, Gach JS, Legasse AW, Axthelm MK, LaBranche CC, Montefiori D, Forthal DN, Park B, Wilson JM, McLinden JH, Xiang J, Stapleton JT, Sacha JB, Haynes BF, Liao HX, Ruprecht RM, Smith J, Gurwith M, Haigwood NL, Alexander J. Malherbe DC, et al. Among authors: haigwood nl. J Virol. 2018 Jan 2;92(2):e01092-17. doi: 10.1128/JVI.01092-17. Print 2018 Jan 15. J Virol. 2018. PMID: 29093095 Free PMC article.
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.
Burwitz BJ, Wettengel JM, Mück-Häusl MA, Ringelhan M, Ko C, Festag MM, Hammond KB, Northrup M, Bimber BN, Jacob T, Reed JS, Norris R, Park B, Moller-Tank S, Esser K, Greene JM, Wu HL, Abdulhaqq S, Webb G, Sutton WF, Klug A, Swanson T, Legasse AW, Vu TQ, Asokan A, Haigwood NL, Protzer U, Sacha JB. Burwitz BJ, et al. Among authors: haigwood nl. Nat Commun. 2017 Dec 15;8(1):2146. doi: 10.1038/s41467-017-01953-y. Nat Commun. 2017. PMID: 29247188 Free PMC article.
Reduced Cell-Associated DNA and Improved Viral Control in Macaques following Passive Transfer of a Single Anti-V2 Monoclonal Antibody and Repeated Simian/Human Immunodeficiency Virus Challenges.
Hessell AJ, Shapiro MB, Powell R, Malherbe DC, McBurney SP, Pandey S, Cheever T, Sutton WF, Kahl C, Park B, Zolla-Pazner S, Haigwood NL. Hessell AJ, et al. Among authors: haigwood nl. J Virol. 2018 May 14;92(11):e02198-17. doi: 10.1128/JVI.02198-17. Print 2018 Jun 1. J Virol. 2018. PMID: 29514914 Free PMC article.
146 results