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24 results

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Page 1
Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a phase 1 study.
Gevaert P, De Craemer J, De Ruyck N, Rottey S, de Hoon J, Hellings PW, Volckaert B, Lesneuck K, Orengo JM, Atanasio A, Kamal MA, Abdallah H, Kamat V, Dingman R, DeVeaux M, Ramesh D, Perlee L, Wang CQ, Weinreich DM, Herman G, Yancopoulos GD, O'Brien MP. Gevaert P, et al. Among authors: perlee l. J Allergy Clin Immunol. 2022 Jan;149(1):189-199. doi: 10.1016/j.jaci.2021.05.039. Epub 2021 Jun 11. J Allergy Clin Immunol. 2022. PMID: 34126156 Free article. Clinical Trial.
Environmental exposure unit simulates natural seasonal birch pollen exposures while maximizing change in allergic symptoms.
Ellis AK, DeVeaux M, Steacy L, Ramesh D, Suprun M, Langdon S, Wang CQ, Adams D, Thiele J, Walker T, Perlee LT, O'Brien MP. Ellis AK, et al. Among authors: perlee lt. Ann Allergy Asthma Immunol. 2021 Oct;127(4):488-495.e5. doi: 10.1016/j.anai.2021.06.015. Epub 2021 Jun 26. Ann Allergy Asthma Immunol. 2021. PMID: 34186172 Free article.
REGN1908/1909 prevented cat allergen-induced early asthmatic responses in an environmental exposure unit.
de Blay FJ, Gherasim A, Domis N, Meier P, Shawki F, Wang CQ, Orengo JM, DeVeaux M, Ramesh D, Jalbert JJ, Kamal MA, Abdallah H, Dingman R, Perlee L, Weinreich DM, Herman G, Yancopoulos GD, O'Brien MP. de Blay FJ, et al. Among authors: perlee l. J Allergy Clin Immunol. 2022 Dec;150(6):1437-1446. doi: 10.1016/j.jaci.2022.06.025. Epub 2022 Aug 4. J Allergy Clin Immunol. 2022. PMID: 35934082 Free article. Clinical Trial.
Large-scale DNA-based typing of HLA-A and HLA-B at low resolution is highly accurate specific and reliable.
Hurley CK, Maiers M, Ng J, Wagage D, Hegland J, Baisch J, Endres R, Fernandez-Vina M, Heine U, Hsu S, Kamoun M, Mitsuishi Y, Monos D, Noreen H, Perlee L, Rodriguez-Marino S, Smith A, Stastny P, Trucco M, Yang SY, Yu N, Holsten R, Hartzman RJ, Setterholm M. Hurley CK, et al. Among authors: perlee l. Tissue Antigens. 2000 Apr;55(4):352-8. doi: 10.1034/j.1399-0039.2000.550409.x. Tissue Antigens. 2000. PMID: 10852387
Validation of DNA-based HLA-A and HLA-B testing of volunteers for a bone marrow registry through parallel testing with serology.
Noreen HJ, Yu N, Setterholm M, Ohashi M, Baisch J, Endres R, Fernandez-Vina M, Heine U, Hsu S, Kamoun M, Mitsuishi Y, Monos D, Perlee L, Rodriguez-Marino S, Smith A, Yang SY, Shipp K, Hegland J, Hurley CK. Noreen HJ, et al. Among authors: perlee l. Tissue Antigens. 2001 Mar;57(3):221-9. doi: 10.1034/j.1399-0039.2001.057003221.x. Tissue Antigens. 2001. PMID: 11285130 Clinical Trial.
Evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy disease: an open-label phase 2 and 3 study.
Ozen A, Chongsrisawat V, Sefer AP, Kolukisa B, Jalbert JJ, Meagher KA, Brackin T, Feldman HB, Baris S, Karakoc-Aydiner E, Ergelen R, Fuss IJ, Moorman H, Suratannon N, Suphapeetiporn K, Perlee L, Harari OA, Yancopoulos GD, Lenardo MJ; Pozelimab CHAPLE Working Group. Ozen A, et al. Among authors: perlee l. Lancet. 2024 Feb 17;403(10427):645-656. doi: 10.1016/S0140-6736(23)02358-9. Epub 2024 Jan 23. Lancet. 2024. PMID: 38278170 Clinical Trial.
24 results