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Page 1
AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC.
Wall EC, Wu M, Harvey R, Kelly G, Warchal S, Sawyer C, Daniels R, Adams L, Hobson P, Hatipoglu E, Ngai Y, Hussain S, Ambrose K, Hindmarsh S, Beale R, Riddell A, Gamblin S, Howell M, Kassiotis G, Libri V, Williams B, Swanton C, Gandhi S, Bauer DL. Wall EC, et al. Among authors: warchal s. Lancet. 2021 Jul 17;398(10296):207-209. doi: 10.1016/S0140-6736(21)01462-8. Epub 2021 Jun 28. Lancet. 2021. PMID: 34197809 Free PMC article. No abstract available.
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.
Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB. Furutani S, et al. Among authors: warchal s. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):350-360. doi: 10.1016/j.ijpddr.2018.06.001. Epub 2018 Jun 4. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29957333 Free PMC article.
Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination.
Wall EC, Wu M, Harvey R, Kelly G, Warchal S, Sawyer C, Daniels R, Hobson P, Hatipoglu E, Ngai Y, Hussain S, Nicod J, Goldstone R, Ambrose K, Hindmarsh S, Beale R, Riddell A, Gamblin S, Howell M, Kassiotis G, Libri V, Williams B, Swanton C, Gandhi S, Bauer DL. Wall EC, et al. Among authors: warchal s. Lancet. 2021 Jun 19;397(10292):2331-2333. doi: 10.1016/S0140-6736(21)01290-3. Epub 2021 Jun 3. Lancet. 2021. PMID: 34090624 Free PMC article. No abstract available.
Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains.
Faulkner N, Ng KW, Wu MY, Harvey R, Margaritis M, Paraskevopoulou S, Houlihan C, Hussain S, Greco M, Bolland W, Warchal S, Heaney J, Rickman H, Spyer M, Frampton D, Byott M, de Oliveira T, Sigal A, Kjaer S, Swanton C, Gandhi S, Beale R, Gamblin SJ, McCauley JW, Daniels RS, Howell M, Bauer D, Nastouli E, Kassiotis G. Faulkner N, et al. Among authors: warchal s. Elife. 2021 Jul 29;10:e69317. doi: 10.7554/eLife.69317. Elife. 2021. PMID: 34323691 Free PMC article.
Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients.
Carr EJ, Wu M, Harvey R, Wall EC, Kelly G, Hussain S, Howell M, Kassiotis G, Swanton C, Gandhi S, Bauer DL; Haemodialysis COVID-19 consortium; Crick COVID Immunity Pipeline; Billany RE, Graham-Brown MP, Beckett J, Bull K, Shankar S, Henderson S, Motallebzadeh R, Salama AD, Harper L, Mark PB, McAdoo S, Willicombe M, Beale R. Carr EJ, et al. Lancet. 2021 Sep 18;398(10305):1038-1041. doi: 10.1016/S0140-6736(21)01854-7. Epub 2021 Aug 13. Lancet. 2021. PMID: 34391504 Free PMC article. No abstract available.
Three-dose vaccination elicits neutralising antibodies against omicron.
Wu M, Wall EC, Carr EJ, Harvey R, Townsley H, Mears HV, Adams L, Kjaer S, Kelly G, Warchal S, Sawyer C, Kavanagh C, Queval CJ, Ngai Y, Hatipoglu E, Ambrose K, Hindmarsh S, Beale R, Gamblin S, Howell M, Kassiotis G, Libri V, Williams B, Gandhi S, Swanton C, Bauer DL. Wu M, et al. Among authors: warchal s. Lancet. 2022 Feb 19;399(10326):715-717. doi: 10.1016/S0140-6736(22)00092-7. Epub 2022 Jan 19. Lancet. 2022. PMID: 35065005 Free PMC article. No abstract available.
Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes.
Tut G, Lancaster T, Krutikov M, Sylla P, Bone D, Spalkova E, Bentley C, Amin U, Jadir A, Hulme S, Kaur N, Tut E, Bruton R, Wu MY, Harvey R, Carr EJ; Crick COVID Immunity Pipeline; Beale R, Stirrup O, Shrotri M, Azmi B, Fuller C, Baynton V, Irwin-Singer A, Hayward A, Copas A, Shallcross L, Moss P. Tut G, et al. Nat Aging. 2023 Jan;3(1):93-104. doi: 10.1038/s43587-022-00328-3. Epub 2023 Jan 20. Nat Aging. 2023. PMID: 37118525 Free PMC article.
Neutralising immunity to omicron sublineages BQ.1.1, XBB, and XBB.1.5 in healthy adults is boosted by bivalent BA.1-containing mRNA vaccination and previous Omicron infection.
Carr EJ, Wu MY, Gahir J, Harvey R, Townsley H, Bailey C, Fowler AS, Dowgier G, Hobbs A, Herman L, Ragno M, Miah M, Bawumia P, Smith C, Miranda M, Mears HV, Adams L, Haptipoglu E, O'Reilly N, Warchal S, Sawyer C, Ambrose K, Kelly G, Beale R, Papineni P, Corrah T, Gilson R, Gamblin S, Kassiotis G, Libri V, Williams B, Swanton C, Gandhi S, Lv Bauer D, Wall EC; Crick COVID Serology Consortium. Carr EJ, et al. Among authors: warchal s. Lancet Infect Dis. 2023 Jul;23(7):781-784. doi: 10.1016/S1473-3099(23)00289-X. Epub 2023 Jun 5. Lancet Infect Dis. 2023. PMID: 37290472 Free PMC article. No abstract available.
Next-generation phenotypic screening.
Warchal SJ, Unciti-Broceta A, Carragher NO. Warchal SJ, et al. Future Med Chem. 2016 Jul;8(11):1331-47. doi: 10.4155/fmc-2016-0025. Epub 2016 Jun 30. Future Med Chem. 2016. PMID: 27357617 Review.
17 results