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Embryo-scale, single-cell spatial transcriptomics.
Srivatsan SR, Regier MC, Barkan E, Franks JM, Packer JS, Grosjean P, Duran M, Saxton S, Ladd JJ, Spielmann M, Lois C, Lampe PD, Shendure J, Stevens KR, Trapnell C. Srivatsan SR, et al. Among authors: spielmann m. Science. 2021 Jul 2;373(6550):111-117. doi: 10.1126/science.abb9536. Science. 2021. PMID: 34210887 Free PMC article.
The single-cell transcriptional landscape of mammalian organogenesis.
Cao J, Spielmann M, Qiu X, Huang X, Ibrahim DM, Hill AJ, Zhang F, Mundlos S, Christiansen L, Steemers FJ, Trapnell C, Shendure J. Cao J, et al. Among authors: spielmann m. Nature. 2019 Feb;566(7745):496-502. doi: 10.1038/s41586-019-0969-x. Epub 2019 Feb 20. Nature. 2019. PMID: 30787437 Free PMC article.
A human cell atlas of fetal gene expression.
Cao J, O'Day DR, Pliner HA, Kingsley PD, Deng M, Daza RM, Zager MA, Aldinger KA, Blecher-Gonen R, Zhang F, Spielmann M, Palis J, Doherty D, Steemers FJ, Glass IA, Trapnell C, Shendure J. Cao J, et al. Among authors: spielmann m. Science. 2020 Nov 13;370(6518):eaba7721. doi: 10.1126/science.aba7721. Science. 2020. PMID: 33184181 Free PMC article.
Systematic reconstruction of cellular trajectories across mouse embryogenesis.
Qiu C, Cao J, Martin BK, Li T, Welsh IC, Srivatsan S, Huang X, Calderon D, Noble WS, Disteche CM, Murray SA, Spielmann M, Moens CB, Trapnell C, Shendure J. Qiu C, et al. Among authors: spielmann m. Nat Genet. 2022 Mar;54(3):328-341. doi: 10.1038/s41588-022-01018-x. Epub 2022 Mar 14. Nat Genet. 2022. PMID: 35288709 Free PMC article.
Single-cell, whole-embryo phenotyping of mammalian developmental disorders.
Huang X, Henck J, Qiu C, Sreenivasan VKA, Balachandran S, Amarie OV, Hrabě de Angelis M, Behncke RY, Chan WL, Despang A, Dickel DE, Duran M, Feuchtinger A, Fuchs H, Gailus-Durner V, Haag N, Hägerling R, Hansmeier N, Hennig F, Marshall C, Rajderkar S, Ringel A, Robson M, Saunders LM, da Silva-Buttkus P, Spielmann N, Srivatsan SR, Ulferts S, Wittler L, Zhu Y, Kalscheuer VM, Ibrahim DM, Kurth I, Kornak U, Visel A, Pennacchio LA, Beier DR, Trapnell C, Cao J, Shendure J, Spielmann M. Huang X, et al. Among authors: spielmann m. Nature. 2023 Nov;623(7988):772-781. doi: 10.1038/s41586-023-06548-w. Epub 2023 Nov 15. Nature. 2023. PMID: 37968388 Free PMC article.
A single-cell time-lapse of mouse prenatal development from gastrula to birth.
Qiu C, Martin BK, Welsh IC, Daza RM, Le TM, Huang X, Nichols EK, Taylor ML, Fulton O, O'Day DR, Gomes AR, Ilcisin S, Srivatsan S, Deng X, Disteche CM, Noble WS, Hamazaki N, Moens CB, Kimelman D, Cao J, Schier AF, Spielmann M, Murray SA, Trapnell C, Shendure J. Qiu C, et al. Among authors: spielmann m. Nature. 2024 Feb;626(8001):1084-1093. doi: 10.1038/s41586-024-07069-w. Epub 2024 Feb 14. Nature. 2024. PMID: 38355799 Free PMC article.
The role of single-cell genomics in human genetics.
Sreenivasan VKA, Balachandran S, Spielmann M. Sreenivasan VKA, et al. Among authors: spielmann m. J Med Genet. 2022 Sep;59(9):827-839. doi: 10.1136/jmedgenet-2022-108588. Epub 2022 Jul 5. J Med Genet. 2022. PMID: 35790352 Free PMC article. Review.
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić S, Prada-Medina CA, Landoulsi Z, Ghelfi J, Delcambre S, Dietrich C, Jarazo J, Henck J, Balachandran S, Pachchek S, Morris CM, Antony P, Timmermann B, Sauer S, Pereira SL, Schwamborn JC, May P, Grünewald A, Spielmann M. Smajić S, et al. Among authors: spielmann m. Brain. 2022 Apr 29;145(3):964-978. doi: 10.1093/brain/awab446. Brain. 2022. PMID: 34919646 Free PMC article.
Single-Cell Sequencing in Neurodegenerative Disorders.
Pozojevic J, Spielmann M. Pozojevic J, et al. Among authors: spielmann m. Mol Diagn Ther. 2023 Sep;27(5):553-561. doi: 10.1007/s40291-023-00668-9. Epub 2023 Aug 8. Mol Diagn Ther. 2023. PMID: 37552451 Free PMC article. Review.
315 results