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Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Zhang Q, Ju B, Ge J, Chan JF, Cheng L, Wang R, Huang W, Fang M, Chen P, Zhou B, Song S, Shan S, Yan B, Zhang S, Ge X, Yu J, Zhao J, Wang H, Liu L, Lv Q, Fu L, Shi X, Yuen KY, Liu L, Wang Y, Chen Z, Zhang L, Wang X, Zhang Z. Zhang Q, et al. Among authors: chan jf. Nat Commun. 2021 Jul 9;12(1):4210. doi: 10.1038/s41467-021-24514-w. Nat Commun. 2021. PMID: 34244522 Free PMC article.
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.
Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. Yuan S, et al. Among authors: chan jf, chan cc, chan ih. Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x. Nat Commun. 2019. PMID: 30631056 Free PMC article.
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study.
To KK, Tsang OT, Leung WS, Tam AR, Wu TC, Lung DC, Yip CC, Cai JP, Chan JM, Chik TS, Lau DP, Choi CY, Chen LL, Chan WM, Chan KH, Ip JD, Ng AC, Poon RW, Luo CT, Cheng VC, Chan JF, Hung IF, Chen Z, Chen H, Yuen KY. To KK, et al. Among authors: chan jf, chan kh, chan jm, chan wm. Lancet Infect Dis. 2020 May;20(5):565-574. doi: 10.1016/S1473-3099(20)30196-1. Epub 2020 Mar 23. Lancet Infect Dis. 2020. PMID: 32213337 Free PMC article.
Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility.
Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY. Chan JF, et al. Among authors: chan kh, chan cc, chan wm. Clin Infect Dis. 2020 Dec 3;71(9):2428-2446. doi: 10.1093/cid/ciaa325. Clin Infect Dis. 2020. PMID: 32215622 Free PMC article.
Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.
Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Hou Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Cai JP, Zhou J, Yuan S, Kok KH, To KK, Chan IH, Zhang AJ, Sit KY, Au WK, Yuen KY. Chu H, et al. Among authors: chan jf, chan ih. Clin Infect Dis. 2020 Sep 12;71(6):1400-1409. doi: 10.1093/cid/ciaa410. Clin Infect Dis. 2020. PMID: 32270184 Free PMC article.
Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction.
Lau SY, Wang P, Mok BW, Zhang AJ, Chu H, Lee AC, Deng S, Chen P, Chan KH, Song W, Chen Z, To KK, Chan JF, Yuen KY, Chen H. Lau SY, et al. Among authors: chan jf, chan kh. Emerg Microbes Infect. 2020 Dec;9(1):837-842. doi: 10.1080/22221751.2020.1756700. Emerg Microbes Infect. 2020. PMID: 32301390 Free PMC article.
Infection of bat and human intestinal organoids by SARS-CoV-2.
Zhou J, Li C, Liu X, Chiu MC, Zhao X, Wang D, Wei Y, Lee A, Zhang AJ, Chu H, Cai JP, Yip CC, Chan IH, Wong KK, Tsang OT, Chan KH, Chan JF, To KK, Chen H, Yuen KY. Zhou J, et al. Among authors: chan jf, chan kh, chan ih. Nat Med. 2020 Jul;26(7):1077-1083. doi: 10.1038/s41591-020-0912-6. Epub 2020 May 13. Nat Med. 2020. PMID: 32405028
381 results