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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Gastroenterology. 2021 Nov;161(5):1584-1600. doi: 10.1053/j.gastro.2021.06.045. Epub 2021 Jul 8.
Gastroenterology. 2021.
PMID: 34245764
Free PMC article.
SIRT1-NOX4 signaling axis regulates cancer cachexia.
Dasgupta A, Shukla SK, Vernucci E, King RJ, Abrego J, Mulder SE, Mullen NJ, Graves G, Buettner K, Thakur R, Murthy D, Attri KS, Wang D, Chaika NV, Pacheco CG, Rai I, Engle DD, Grandgenett PM, Punsoni M, Reames BN, Teoh-Fitzgerald M, Oberley-Deegan R, Yu F, Klute KA, Hollingsworth MA, Zimmerman MC, Mehla K, Sadoshima J, Tuveson DA, Singh PK.
Dasgupta A, et al. Among authors: mullen nj.
J Exp Med. 2020 Jul 6;217(7):e20190745. doi: 10.1084/jem.20190745.
J Exp Med. 2020.
PMID: 32441762
Free PMC article.
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ENT1 blockade by CNX-774 overcomes resistance to DHODH inhibition in pancreatic cancer.
Mullen NJ, Thakur R, Shukla SK, Chaika NV, Kollala SS, Wang D, He C, Fujii Y, Sharma S, Mulder SE, Sykes DB, Singh PK.
Mullen NJ, et al.
Cancer Lett. 2023 Jan 1;552:215981. doi: 10.1016/j.canlet.2022.215981. Epub 2022 Oct 27.
Cancer Lett. 2023.
PMID: 36341997
Free PMC article.
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Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome.
Nilson KA, Lawson CK, Mullen NJ, Ball CB, Spector BM, Meier JL, Price DH.
Nilson KA, et al. Among authors: mullen nj.
Nucleic Acids Res. 2017 Nov 2;45(19):11088-11105. doi: 10.1093/nar/gkx724.
Nucleic Acids Res. 2017.
PMID: 28977633
Free PMC article.
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Hydrogen peroxide yields mechanistic insights into human mRNA capping enzyme function.
Mullen NJ, Price DH.
Mullen NJ, et al.
PLoS One. 2017 Oct 13;12(10):e0186423. doi: 10.1371/journal.pone.0186423. eCollection 2017.
PLoS One. 2017.
PMID: 29028835
Free PMC article.
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DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.
Mullen NJ, Shukla SK, Thakur R, Kollala SS, Wang D, Chaika N, Santana JF, Miklavcic WR, LaBreck DA, Mallareddy JR, Price DH, Natarajan A, Mehla K, Sykes DB, Hollingsworth MA, Singh PK.
Mullen NJ, et al.
bioRxiv [Preprint]. 2024 Jan 13:2023.04.03.535399. doi: 10.1101/2023.04.03.535399.
bioRxiv. 2024.
PMID: 37066260
Free PMC article.
Preprint.
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Nucleotide metabolism: a pan-cancer metabolic dependency.
Mullen NJ, Singh PK.
Mullen NJ, et al.
Nat Rev Cancer. 2023 May;23(5):275-294. doi: 10.1038/s41568-023-00557-7. Epub 2023 Mar 27.
Nat Rev Cancer. 2023.
PMID: 36973407
Free PMC article.
Review.
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Comparison of energy expenditure and heart rate responses between three commercial group fitness classes.
Wickham JB, Mullen NJ, Whyte DG, Cannon J.
Wickham JB, et al. Among authors: mullen nj.
J Sci Med Sport. 2017 Jul;20(7):667-671. doi: 10.1016/j.jsams.2016.11.012. Epub 2017 Jan 24.
J Sci Med Sport. 2017.
PMID: 28185805
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