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Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease.
Nat Commun. 2021 Jul 12;12(1):4246. doi: 10.1038/s41467-021-24470-5.
Nat Commun. 2021.
PMID: 34253728
Free PMC article.
ELMO1 Regulates Autophagy Induction and Bacterial Clearance During Enteric Infection.
Sarkar A, Tindle C, Pranadinata RF, Reed S, Eckmann L, Stappenbeck TS, Ernst PB, Das S.
Sarkar A, et al. Among authors: pranadinata rf.
J Infect Dis. 2017 Dec 19;216(12):1655-1666. doi: 10.1093/infdis/jix528.
J Infect Dis. 2017.
PMID: 29029244
Free PMC article.
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TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin.
Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P.
Swanson L, et al. Among authors: pranadinata rf.
Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26895-26906. doi: 10.1073/pnas.2011667117. Epub 2020 Oct 14.
Proc Natl Acad Sci U S A. 2020.
PMID: 33055214
Free PMC article.
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E-cigarettes compromise the gut barrier and trigger inflammation.
Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF, Ear J, Sahoo D, Crotty-Alexander LE, Ghosh P, Das S.
Sharma A, et al. Among authors: pranadinata rf.
iScience. 2021 Jan 6;24(2):102035. doi: 10.1016/j.isci.2021.102035. eCollection 2021 Feb 19.
iScience. 2021.
PMID: 33537654
Free PMC article.
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The interaction of enteric bacterial effectors with the host engulfment pathway control innate immune responses.
Sayed IM, Ibeawuchi SR, Lie D, Anandachar MS, Pranadinata R, Raffatellu M, Das S.
Sayed IM, et al.
Gut Microbes. 2021 Jan-Dec;13(1):1991776. doi: 10.1080/19490976.2021.1991776.
Gut Microbes. 2021.
PMID: 34719317
Free PMC article.
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JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Ambrus-Aikelin G, Takeda K, Joetham A, Lazic M, Povero D, Santini AM, Pranadinata R, Johnson CD, McGeough MD, Beasley FC, Stansfield R, McBride C, Trzoss L, Hoffman HM, Feldstein AE, Stafford JA, Veal JM, Bain G, Gelfand EW.
Ambrus-Aikelin G, et al.
Sci Rep. 2023 Aug 19;13(1):13524. doi: 10.1038/s41598-023-39805-z.
Sci Rep. 2023.
PMID: 37598239
Free PMC article.
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Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.
Povero D, Lazic M, McBride C, Ambrus-Aikelin G, Stansfield R, Johnson CD, Santini AM, Pranadinata RF, McGeough MD, Stafford JA, Hoffman HM, Feldstein AE, Veal JM, Bain G.
Povero D, et al. Among authors: pranadinata rf.
J Pharmacol Exp Ther. 2023 Aug;386(2):242-258. doi: 10.1124/jpet.123.001639. Epub 2023 Jun 12.
J Pharmacol Exp Ther. 2023.
PMID: 37308266
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A Living Organoid Biobank of Crohn's Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics.
Tindle C, Katkar GD, Fonseca AG, Taheri S, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P.
Tindle C, et al. Among authors: pranadinata rf.
bioRxiv [Preprint]. 2023 Mar 13:2023.03.11.532245. doi: 10.1101/2023.03.11.532245.
bioRxiv. 2023.
PMID: 36993763
Free PMC article.
Preprint.
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