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FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption.
Cell Metab. 2021 Aug 3;33(8):1671-1684.e4. doi: 10.1016/j.cmet.2021.06.012. Epub 2021 Jul 15.
Cell Metab. 2021.
PMID: 34270928
Free PMC article.
ZFP36-mediated mRNA decay regulates metabolism.
Cicchetto AC, Jacobson EC, Sunshine H, Wilde BR, Krall AS, Jarrett KE, Sedgeman L, Turner M, Plath K, Iruela-Arispe ML, de Aguiar Vallim TQ, Christofk HR.
Cicchetto AC, et al.
Cell Rep. 2023 May 30;42(5):112411. doi: 10.1016/j.celrep.2023.112411. Epub 2023 Apr 21.
Cell Rep. 2023.
PMID: 37086408
Free PMC article.
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Intestinal bile acid sequestration improves glucose control by stimulating hepatic miR-182-5p in type 2 diabetes.
Sedgeman LR, Beysen C, Allen RM, Ramirez Solano MA, Turner SM, Vickers KC.
Sedgeman LR, et al.
Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G810-G823. doi: 10.1152/ajpgi.00238.2018. Epub 2018 Aug 30.
Am J Physiol Gastrointest Liver Physiol. 2018.
PMID: 30160993
Free PMC article.
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Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion.
Sedgeman LR, Beysen C, Ramirez Solano MA, Michell DL, Sheng Q, Zhao S, Turner S, Linton MF, Vickers KC.
Sedgeman LR, et al.
Sci Rep. 2019 Mar 7;9(1):3803. doi: 10.1038/s41598-019-40338-7.
Sci Rep. 2019.
PMID: 30846744
Free PMC article.
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Integrative roles of microRNAs in lipid metabolism and dyslipidemia.
Sedgeman LR, Michell DL, Vickers KC.
Sedgeman LR, et al.
Curr Opin Lipidol. 2019 Jun;30(3):165-171. doi: 10.1097/MOL.0000000000000603.
Curr Opin Lipidol. 2019.
PMID: 30985366
Free PMC article.
Review.
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Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, Aamodt KI, Phillips N, Yan H, Bernal-Mizrachi E, Corbin JD, Vickers KC, Levy SE, Dai C, Newgard C, Gu W, Stein R, Chen W, Powers AC.
Dean ED, et al. Among authors: sedgeman lr.
Cell Metab. 2017 Jun 6;25(6):1362-1373.e5. doi: 10.1016/j.cmet.2017.05.011.
Cell Metab. 2017.
PMID: 28591638
Free PMC article.
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Dietary and Pharmacologic Manipulations of Host Lipids and Their Interaction With the Gut Microbiome in Non-human Primates.
Lang JM, Sedgeman LR, Cai L, Layne JD, Wang Z, Pan C, Lee R, Temel RE, Lusis AJ.
Lang JM, et al. Among authors: sedgeman lr.
Front Med (Lausanne). 2021 Aug 26;8:646710. doi: 10.3389/fmed.2021.646710. eCollection 2021.
Front Med (Lausanne). 2021.
PMID: 34513856
Free PMC article.
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