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FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption.
Clifford BL, Sedgeman LR, Williams KJ, Morand P, Cheng A, Jarrett KE, Chan AP, Brearley-Sholto MC, Wahlström A, Ashby JW, Barshop W, Wohlschlegel J, Calkin AC, Liu Y, Thorell A, Meikle PJ, Drew BG, Mack JJ, Marschall HU, Tarling EJ, Edwards PA, de Aguiar Vallim TQ. Clifford BL, et al. Among authors: thorell a. Cell Metab. 2021 Aug 3;33(8):1671-1684.e4. doi: 10.1016/j.cmet.2021.06.012. Epub 2021 Jul 15. Cell Metab. 2021. PMID: 34270928 Free PMC article.
Impact of gastroesophageal reflux control through tailored proton pump inhibition therapy or fundoplication in patients with Barrett's esophagus.
Baldaque-Silva F, Vieth M, Debel M, Håkanson B, Thorell A, Lunet N, Song H, Mascarenhas-Saraiva M, Pereira G, Lundell L, Marschall HU. Baldaque-Silva F, et al. Among authors: thorell a. World J Gastroenterol. 2017 May 7;23(17):3174-3183. doi: 10.3748/wjg.v23.i17.3174. World J Gastroenterol. 2017. PMID: 28533674 Free PMC article.
FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
Panzitt K, Jungwirth E, Krones E, Lee JM, Pollheimer M, Thallinger GG, Kolb-Lenz D, Xiao R, Thorell A, Trauner M, Fickert P, Marschall HU, Moore DD, Wagner M. Panzitt K, et al. Among authors: thorell a. J Hepatol. 2020 Jun;72(6):1122-1131. doi: 10.1016/j.jhep.2020.01.014. Epub 2020 Jan 28. J Hepatol. 2020. PMID: 32001325 Free article.
Retained NK Cell Phenotype and Functionality in Non-alcoholic Fatty Liver Disease.
Stiglund N, Strand K, Cornillet M, Stål P, Thorell A, Zimmer CL, Näslund E, Karlgren S, Nilsson H, Mellgren G, Fernø J, Hagström H, Björkström NK. Stiglund N, et al. Among authors: thorell a. Front Immunol. 2019 Jun 4;10:1255. doi: 10.3389/fimmu.2019.01255. eCollection 2019. Front Immunol. 2019. PMID: 31214196 Free PMC article.
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance.
Azzimato V, Jager J, Chen P, Morgantini C, Levi L, Barreby E, Sulen A, Oses C, Willerbrords J, Xu C, Li X, Shen JX, Akbar N, Haag L, Ellis E, Wålhen K, Näslund E, Thorell A, Choudhury RP, Lauschke VM, Rydén M, Craige SM, Aouadi M. Azzimato V, et al. Among authors: thorell a. Sci Transl Med. 2020 Feb 26;12(532):eaaw9709. doi: 10.1126/scitranslmed.aaw9709. Sci Transl Med. 2020. PMID: 32102936
234 results