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Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease.
Ban T, Kikuchi M, Sato GR, Manabe A, Tagata N, Harita K, Nishiyama A, Nishimura K, Yoshimi R, Kirino Y, Yanai H, Matsumoto Y, Suzuki S, Hihara H, Ito M, Tsukahara K, Yoshimatsu K, Yamamoto T, Taniguchi T, Nakajima H, Ito S, Tamura T. Ban T, et al. Among authors: suzuki s. Nat Commun. 2021 Jul 19;12(1):4379. doi: 10.1038/s41467-021-24609-4. Nat Commun. 2021. PMID: 34282144 Free PMC article.
Thieno[2,3-d]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1).
Berhane I, Hin N, Thomas AG, Huang Q, Zhang C, Veeravalli V, Wu Y, Ng J, Alt J, Rojas C, Hihara H, Aoki M, Yoshizawa K, Nishioka T, Suzuki S, He SQ, Peng Q, Guan Y, Dong X, Raja SN, Slusher BS, Rais R, Tsukamoto T. Berhane I, et al. Among authors: suzuki s. J Med Chem. 2022 Feb 24;65(4):3218-3228. doi: 10.1021/acs.jmedchem.1c01709. Epub 2022 Feb 4. J Med Chem. 2022. PMID: 35119273 Free PMC article.
Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists.
Prchalová E, Hin N, Thomas AG, Veeravalli V, Ng J, Alt J, Rais R, Rojas C, Li Z, Hihara H, Aoki M, Yoshizawa K, Nishioka T, Suzuki S, Kopajtic T, Chatrath S, Liu Q, Dong X, Slusher BS, Tsukamoto T. Prchalová E, et al. Among authors: suzuki s. J Med Chem. 2019 Sep 26;62(18):8631-8641. doi: 10.1021/acs.jmedchem.9b01003. Epub 2019 Sep 9. J Med Chem. 2019. PMID: 31498617 Free PMC article.
Ago-allosteric modulators of human glucagon-like peptide 2 receptor.
Yamazaki K, Terauchi H, Iida D, Fukumoto H, Suzuki S, Kagaya T, Aoki M, Koyama K, Seiki T, Takase K, Watanabe M, Arai T, Tsukahara K, Nagakawa J. Yamazaki K, et al. Among authors: suzuki s. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6126-35. doi: 10.1016/j.bmcl.2012.08.026. Epub 2012 Aug 14. Bioorg Med Chem Lett. 2012. PMID: 22944117
The novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial thrombosis without affecting bleeding time in guinea pigs.
Kogushi M, Matsuoka T, Kawata T, Kuramochi H, Kawaguchi S, Murakami K, Hiyoshi H, Suzuki S, Kawahara T, Kajiwara A, Hishinuma I. Kogushi M, et al. Among authors: suzuki s. Eur J Pharmacol. 2011 Apr 25;657(1-3):131-7. doi: 10.1016/j.ejphar.2011.01.058. Epub 2011 Feb 4. Eur J Pharmacol. 2011. PMID: 21300059
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