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Study protocol for a phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous meningitis [LASER-TBM].
Davis AG, Wasserman S, Maxebengula M, Stek C, Bremer M, Daroowala R, Aziz S, Goliath R, Stegmann S, Koekemoer S, Jackson A, Lai Sai L, Kadernani Y, Sihoyiya T, Liang CJ, Dodd L, Denti P, Crede T, Naude J, Szymanski P, Vallie Y, Banderker I, Moosa S, Raubenheimer P, Lai RPJ, Joska J, Nightingale S, Dreyer A, Wahl G, Offiah C, Vorster I, Candy S, Robertson F, Meintjes E, Maartens G, Black J, Meintjes G, Wilkinson RJ. Davis AG, et al. Among authors: dodd l. Wellcome Open Res. 2021 Jun 1;6:136. doi: 10.12688/wellcomeopenres.16783.1. eCollection 2021. Wellcome Open Res. 2021. PMID: 34286103 Free PMC article.
Isoniazid preventive therapy in HIV infection.
Dodd LE, Wilkinson RJ. Dodd LE, et al. Lancet. 2011 May 7;377(9777):1548-50. doi: 10.1016/S0140-6736(11)60434-0. Epub 2011 Apr 12. Lancet. 2011. PMID: 21492928 No abstract available.
Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial.
Chen RY, Via LE, Dodd LE, Walzl G, Malherbe ST, Loxton AG, Dawson R, Wilkinson RJ, Thienemann F, Tameris M, Hatherill M, Diacon AH, Liu X, Xing J, Jin X, Ma Z, Pan S, Zhang G, Gao Q, Jiang Q, Zhu H, Liang L, Duan H, Song T, Alland D, Tartakovsky M, Rosenthal A, Whalen C, Duvenhage M, Cai Y, Goldfeder LC, Arora K, Smith B, Winter J, Barry Iii CE; Predict TB Study Group. Chen RY, et al. Among authors: dodd le. Gates Open Res. 2017 Nov 6;1:9. doi: 10.12688/gatesopenres.12750.1. Gates Open Res. 2017. PMID: 29528048 Free PMC article.
A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images.
Malherbe ST, Dupont P, Kant I, Ahlers P, Kriel M, Loxton AG, Chen RY, Via LE, Thienemann F, Wilkinson RJ, Barry CE 3rd, Griffith-Richards S, Ellman A, Ronacher K, Winter J, Walzl G, Warwick JM; Catalysis Biomarker Consortium. Malherbe ST, et al. EJNMMI Res. 2018 Jun 25;8(1):55. doi: 10.1186/s13550-018-0411-7. EJNMMI Res. 2018. PMID: 29943161 Free PMC article.
Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis.
Xie YL, de Jager VR, Chen RY, Dodd LE, Paripati P, Via LE, Follmann D, Wang J, Lumbard K, Lahouar S, Malherbe ST, Andrews J, Yu X, Goldfeder LC, Cai Y, Arora K, Loxton AG, Vanker N, Duvenhage M, Winter J, Song T, Walzl G, Diacon AH, Barry CE 3rd. Xie YL, et al. Among authors: dodd le. Sci Transl Med. 2021 Feb 3;13(579):eabd7618. doi: 10.1126/scitranslmed.abd7618. Sci Transl Med. 2021. PMID: 33536283 Free PMC article.
The Peripheral Blood Transcriptome Is Correlated With PET Measures of Lung Inflammation During Successful Tuberculosis Treatment.
Odia T, Malherbe ST, Meier S, Maasdorp E, Kleynhans L, du Plessis N, Loxton AG, Zak DE, Thompson E, Duffy FJ, Kuivaniemi H, Ronacher K, Winter J, Walzl G, Tromp G; Catalysis TB-Biomarker Consortium. Odia T, et al. Front Immunol. 2021 Feb 10;11:596173. doi: 10.3389/fimmu.2020.596173. eCollection 2020. Front Immunol. 2021. PMID: 33643286 Free PMC article.
Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis.
Song T, Lee M, Jeon HS, Park Y, Dodd LE, Dartois V, Follman D, Wang J, Cai Y, Goldfeder LC, Olivier KN, Xie Y, Via LE, Cho SN, Barry CE 3rd, Chen RY. Song T, et al. EBioMedicine. 2015 Oct 9;2(11):1627-33. doi: 10.1016/j.ebiom.2015.09.051. eCollection 2015 Nov. EBioMedicine. 2015. PMID: 26870788 Free PMC article. Clinical Trial.
A sterilizing tuberculosis treatment regimen is associated with faster clearance of bacteria in cavitary lesions in marmosets.
Via LE, England K, Weiner DM, Schimel D, Zimmerman MD, Dayao E, Chen RY, Dodd LE, Richardson M, Robbins KK, Cai Y, Hammoud D, Herscovitch P, Dartois V, Flynn JL, Barry CE 3rd. Via LE, et al. Among authors: dodd le. Antimicrob Agents Chemother. 2015 Jul;59(7):4181-9. doi: 10.1128/AAC.00115-15. Epub 2015 May 4. Antimicrob Agents Chemother. 2015. PMID: 25941223 Free PMC article.
481 results