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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.
Geuijen C, Tacken P, Wang LC, Klooster R, van Loo PF, Zhou J, Mondal A, Liu YB, Kramer A, Condamine T, Volgina A, Hendriks LJA, van der Maaden H, Rovers E, Engels S, Fransen F, den Blanken-Smit R, Zondag-van der Zande V, Basmeleh A, Bartelink W, Kulkarni A, Marissen W, Huang CY, Hall L, Harvey S, Kim S, Martinez M, O'Brien S, Moon E, Albelda S, Kanellopoulou C, Stewart S, Nastri H, Bakker ABH, Scherle P, Logtenberg T, Hollis G, de Kruif J, Huber R, Mayes PA, Throsby M. Geuijen C, et al. Among authors: kramer a. Nat Commun. 2021 Jul 21;12(1):4445. doi: 10.1038/s41467-021-24767-5. Nat Commun. 2021. PMID: 34290245 Free PMC article.
MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis.
van Loo PF, Hangalapura BN, Thordardottir S, Gibbins JD, Veninga H, Hendriks LJA, Kramer A, Roovers RC, Leenders M, de Kruif J, Doornbos RP, Sirulnik A, Throsby M, Logtenberg T, Dolstra H, Bakker ABH. van Loo PF, et al. Among authors: kramer a. Expert Opin Biol Ther. 2019 Jul;19(7):721-733. doi: 10.1080/14712598.2019.1623200. Expert Opin Biol Ther. 2019. PMID: 31286786
Generation of stable cell clones expressing mixtures of human antibodies.
de Kruif J, Kramer A, Nijhuis R, van der Zande V, den Blanken R, Clements C, Visser T, Keehnen R, den Hartog M, Throsby M, Logtenberg T. de Kruif J, et al. Among authors: kramer a. Biotechnol Bioeng. 2010 Aug 1;106(5):741-50. doi: 10.1002/bit.22763. Biotechnol Bioeng. 2010. PMID: 20564612
Physical exercise, cognition, and brain health in aging.
Boa Sorte Silva NC, Barha CK, Erickson KI, Kramer AF, Liu-Ambrose T. Boa Sorte Silva NC, et al. Among authors: kramer af. Trends Neurosci. 2024 May 28:S0166-2236(24)00062-6. doi: 10.1016/j.tins.2024.04.004. Online ahead of print. Trends Neurosci. 2024. PMID: 38811309 Review.
Intensive Care Unit Staffing in the United States.
Gershengorn HB, Garland A, Costa DK, Dzierba AL, Fowler R, Kramer AA, Liu VX, Lizano D, Scales DC, Wunsch H. Gershengorn HB, et al. Among authors: kramer aa. Chest. 2024 May 22:S0012-3692(24)00631-7. doi: 10.1016/j.chest.2024.04.012. Online ahead of print. Chest. 2024. PMID: 38788896
2,985 results