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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.
Geuijen C, Tacken P, Wang LC, Klooster R, van Loo PF, Zhou J, Mondal A, Liu YB, Kramer A, Condamine T, Volgina A, Hendriks LJA, van der Maaden H, Rovers E, Engels S, Fransen F, den Blanken-Smit R, Zondag-van der Zande V, Basmeleh A, Bartelink W, Kulkarni A, Marissen W, Huang CY, Hall L, Harvey S, Kim S, Martinez M, O'Brien S, Moon E, Albelda S, Kanellopoulou C, Stewart S, Nastri H, Bakker ABH, Scherle P, Logtenberg T, Hollis G, de Kruif J, Huber R, Mayes PA, Throsby M. Geuijen C, et al. Among authors: wang lc. Nat Commun. 2021 Jul 21;12(1):4445. doi: 10.1038/s41467-021-24767-5. Nat Commun. 2021. PMID: 34290245 Free PMC article.
Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors.
Moon EK, Wang LC, Dolfi DV, Wilson CB, Ranganathan R, Sun J, Kapoor V, Scholler J, Puré E, Milone MC, June CH, Riley JL, Wherry EJ, Albelda SM. Moon EK, et al. Among authors: wang lc. Clin Cancer Res. 2014 Aug 15;20(16):4262-73. doi: 10.1158/1078-0432.CCR-13-2627. Epub 2014 Jun 11. Clin Cancer Res. 2014. PMID: 24919573 Free PMC article.
The receptor for advanced glycation end products mediates lung endothelial activation by RBCs.
Mangalmurti NS, Friedman JL, Wang LC, Stolz D, Muthukumaran G, Siegel DL, Schmidt AM, Lee JS, Albelda SM. Mangalmurti NS, et al. Among authors: wang lc. Am J Physiol Lung Cell Mol Physiol. 2013 Feb 15;304(4):L250-63. doi: 10.1152/ajplung.00278.2012. Epub 2012 Dec 28. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23275625 Free PMC article.
Mesothelin, a novel immunotherapy target for triple negative breast cancer.
Tchou J, Wang LC, Selven B, Zhang H, Conejo-Garcia J, Borghaei H, Kalos M, Vondeheide RH, Albelda SM, June CH, Zhang PJ. Tchou J, et al. Among authors: wang lc. Breast Cancer Res Treat. 2012 Jun;133(2):799-804. doi: 10.1007/s10549-012-2018-4. Epub 2012 Mar 15. Breast Cancer Res Treat. 2012. PMID: 22418702 Free PMC article.
Thymidylate synthase and folyl-polyglutamate synthase are not clinically useful markers of response to pemetrexed in patients with malignant pleural mesothelioma.
Lustgarten DE, Deshpande C, Aggarwal C, Wang LC, Saloura V, Vachani A, Wang LP, Litzky L, Feldman M, Creaney J, Nowak AK, Langer C, Inghilleri S, Stella G, Albelda SM. Lustgarten DE, et al. Among authors: wang lp, wang lc. J Thorac Oncol. 2013 Apr;8(4):469-77. doi: 10.1097/JTO.0b013e318283da3e. J Thorac Oncol. 2013. PMID: 23486267 Free PMC article.
1,259 results