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Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia.
Sartori R, Hagg A, Zampieri S, Armani A, Winbanks CE, Viana LR, Haidar M, Watt KI, Qian H, Pezzini C, Zanganeh P, Turner BJ, Larsson A, Zanchettin G, Pierobon ES, Moletta L, Valmasoni M, Ponzoni A, Attar S, Da Dalt G, Sperti C, Kustermann M, Thomson RE, Larsson L, Loveland KL, Costelli P, Megighian A, Merigliano S, Penna F, Gregorevic P, Sandri M. Sartori R, et al. Among authors: gregorevic p. Sci Transl Med. 2021 Aug 4;13(605):eaay9592. doi: 10.1126/scitranslmed.aay9592. Sci Transl Med. 2021. PMID: 34349036
Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin.
Winbanks CE, Weeks KL, Thomson RE, Sepulveda PV, Beyer C, Qian H, Chen JL, Allen JM, Lancaster GI, Febbraio MA, Harrison CA, McMullen JR, Chamberlain JS, Gregorevic P. Winbanks CE, et al. Among authors: gregorevic p. J Cell Biol. 2012 Jun 25;197(7):997-1008. doi: 10.1083/jcb.201109091. Epub 2012 Jun 18. J Cell Biol. 2012. PMID: 22711699 Free PMC article.
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function.
Bernardo BC, Gao XM, Winbanks CE, Boey EJ, Tham YK, Kiriazis H, Gregorevic P, Obad S, Kauppinen S, Du XJ, Lin RC, McMullen JR. Bernardo BC, et al. Among authors: gregorevic p. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17615-20. doi: 10.1073/pnas.1206432109. Epub 2012 Oct 9. Proc Natl Acad Sci U S A. 2012. PMID: 23047694 Free PMC article.
The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass.
Winbanks CE, Chen JL, Qian H, Liu Y, Bernardo BC, Beyer C, Watt KI, Thomson RE, Connor T, Turner BJ, McMullen JR, Larsson L, McGee SL, Harrison CA, Gregorevic P. Winbanks CE, et al. Among authors: gregorevic p. J Cell Biol. 2013 Oct 28;203(2):345-57. doi: 10.1083/jcb.201211134. Epub 2013 Oct 21. J Cell Biol. 2013. PMID: 24145169 Free PMC article.
Elevated expression of activins promotes muscle wasting and cachexia.
Chen JL, Walton KL, Winbanks CE, Murphy KT, Thomson RE, Makanji Y, Qian H, Lynch GS, Harrison CA, Gregorevic P. Chen JL, et al. Among authors: gregorevic p. FASEB J. 2014 Apr;28(4):1711-23. doi: 10.1096/fj.13-245894. Epub 2013 Dec 30. FASEB J. 2014. PMID: 24378873
129 results