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GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Kremer DM, et al. Among authors: shah ym. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. Nat Commun. 2021. PMID: 34381026 Free PMC article.
Pancreatic HIF2α Stabilization Leads to Chronic Pancreatitis and Predisposes to Mucinous Cystic Neoplasm.
Schofield HK, Tandon M, Park MJ, Halbrook CJ, Ramakrishnan SK, Kim EC, Shi J, Omary MB, Shah YM, Esni F, Pasca di Magliano M. Schofield HK, et al. Among authors: shah ym. Cell Mol Gastroenterol Hepatol. 2017 Nov 10;5(2):169-185.e2. doi: 10.1016/j.jcmgh.2017.10.008. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29693047 Free PMC article.
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM. Ramakrishnan SK, et al. Among authors: shah ym. Nat Commun. 2019 Feb 8;10(1):660. doi: 10.1038/s41467-019-08581-8. Nat Commun. 2019. PMID: 30737385 Free PMC article.
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis.
Das NK, Schwartz AJ, Barthel G, Inohara N, Liu Q, Sankar A, Hill DR, Ma X, Lamberg O, Schnizlein MK, Arqués JL, Spence JR, Nunez G, Patterson AD, Sun D, Young VB, Shah YM. Das NK, et al. Among authors: shah ym. Cell Metab. 2020 Jan 7;31(1):115-130.e6. doi: 10.1016/j.cmet.2019.10.005. Epub 2019 Nov 7. Cell Metab. 2020. PMID: 31708445 Free PMC article.
183 results