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GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Kremer DM, et al. Among authors: di magliano mp. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. Nat Commun. 2021. PMID: 34381026 Free PMC article.
ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis.
Wang L, Yang H, Zamperone A, Diolaiti D, Palmbos PL, Abel EV, Purohit V, Dolgalev I, Rhim AD, Ljungman M, Hadju CH, Halbrook CJ, Bar-Sagi D, di Magliano MP, Crawford HC, Simeone DM. Wang L, et al. Among authors: di magliano mp. Genes Dev. 2019 Jun 1;33(11-12):641-655. doi: 10.1101/gad.323303.118. Epub 2019 May 2. Genes Dev. 2019. PMID: 31048544 Free PMC article.
Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis.
Wen HJ, Gao S, Wang Y, Ray M, Magnuson MA, Wright CVE, Di Magliano MP, Frankel TL, Crawford HC. Wen HJ, et al. Among authors: di magliano mp. Cell Mol Gastroenterol Hepatol. 2019;8(2):173-192. doi: 10.1016/j.jcmgh.2019.05.006. Epub 2019 May 21. Cell Mol Gastroenterol Hepatol. 2019. PMID: 31125624 Free PMC article.
Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance.
Nwosu ZC, Piorońska W, Battello N, Zimmer AD, Dewidar B, Han M, Pereira S, Blagojevic B, Castven D, Charlestin V, Holenya P, Lochead J, De La Torre C, Gretz N, Sajjakulnukit P, Zhang L, Ward MH, Marquardt JU, di Magliano MP, Lyssiotis CA, Sleeman J, Wölfl S, Ebert MP, Meyer C, Hofmann U, Dooley S. Nwosu ZC, et al. Among authors: di magliano mp. EBioMedicine. 2020 Apr;54:102699. doi: 10.1016/j.ebiom.2020.102699. Epub 2020 Apr 21. EBioMedicine. 2020. PMID: 32330875 Free PMC article.
Immunotherapy for pancreatic ductal adenocarcinoma.
Carpenter E, Nelson S, Bednar F, Cho C, Nathan H, Sahai V, di Magliano MP, Frankel TL. Carpenter E, et al. Among authors: di magliano mp. J Surg Oncol. 2021 Mar;123(3):751-759. doi: 10.1002/jso.26312. J Surg Oncol. 2021. PMID: 33595893 Review.
KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity.
Lu S, Kim HS, Cao Y, Bedi K, Zhao L, Narayanan IV, Magnuson B, Gu Y, Yang J, Yi Z, Babaniamansour S, Shameon S, Xu C, Paulsen MT, Qiu P, Jeyarajan S, Ljungman M, Thomas D, Dou Y, Crawford H, di Magliano MP, Ge K, Yang B, Shi J. Lu S, et al. Among authors: di magliano mp. Int J Cancer. 2023 Aug 1;153(3):552-570. doi: 10.1002/ijc.34528. Epub 2023 May 4. Int J Cancer. 2023. PMID: 37140208
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M. Thayer SP, et al. Among authors: di magliano mp. Nature. 2003 Oct 23;425(6960):851-6. doi: 10.1038/nature02009. Epub 2003 Sep 14. Nature. 2003. PMID: 14520413 Free PMC article.
38 results