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Multiplexed detection of SARS-CoV-2 genomic and subgenomic RNA using in situ hybridization.
Acheampong KK, Schaff DL, Emert BL, Lake J, Reffsin S, Shea EK, Comar CE, Litzky LA, Khurram NA, Linn RL, Feldman M, Weiss SR, Montone KT, Cherry S, Shaffer SM. Acheampong KK, et al. Among authors: shaffer sm. bioRxiv [Preprint]. 2021 Aug 11:2021.08.11.455959. doi: 10.1101/2021.08.11.455959. bioRxiv. 2021. PMID: 34401878 Free PMC article. Preprint.
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.
Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, Herlyn M, Raj A. Shaffer SM, et al. Nature. 2017 Jun 15;546(7658):431-435. doi: 10.1038/nature22794. Epub 2017 Jun 7. Nature. 2017. PMID: 28607484 Free PMC article.
Genetic screening for single-cell variability modulators driving therapy resistance.
Torre EA, Arai E, Bayatpour S, Jiang CL, Beck LE, Emert BL, Shaffer SM, Mellis IA, Fane ME, Alicea GM, Budinich KA, Weeraratna AT, Shi J, Raj A. Torre EA, et al. Among authors: shaffer sm. Nat Genet. 2021 Jan;53(1):76-85. doi: 10.1038/s41588-020-00749-z. Epub 2021 Jan 4. Nat Genet. 2021. PMID: 33398196 Free PMC article.
Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages.
Acheampong KK, Schaff DL, Emert BL, Lake J, Reffsin S, Shea EK, Comar CE, Litzky LA, Khurram NA, Linn RL, Feldman M, Weiss SR, Montone KT, Cherry S, Shaffer SM. Acheampong KK, et al. Among authors: shaffer sm. mBio. 2021 Feb 22;13(1):e0375121. doi: 10.1128/mbio.03751-21. Epub 2022 Feb 8. mBio. 2021. PMID: 35130722 Free PMC article.
Clonal cell states link Barrett's esophagus and esophageal adenocarcinoma.
Gier RA, Hueros RAR, Rong J, DeMarshall M, Karakasheva TA, Muir AB, Falk GW, Zhang NR, Shaffer SM. Gier RA, et al. Among authors: shaffer sm. bioRxiv [Preprint]. 2023 Feb 6:2023.01.26.525564. doi: 10.1101/2023.01.26.525564. bioRxiv. 2023. PMID: 36747708 Free PMC article. Preprint.
Disrupting cellular memory to overcome drug resistance.
Harmange G, Hueros RAR, Schaff DL, Emert B, Saint-Antoine M, Kim LC, Niu Z, Nellore S, Fane ME, Alicea GM, Weeraratna AT, Simon MC, Singh A, Shaffer SM. Harmange G, et al. Among authors: shaffer sm. Nat Commun. 2023 Nov 6;14(1):7130. doi: 10.1038/s41467-023-41811-8. Nat Commun. 2023. PMID: 37932277 Free PMC article.
Author Correction: Disrupting cellular memory to overcome drug resistance.
Harmange G, Hueros RAR, Schaff DL, Emert B, Saint-Antoine M, Kim LC, Niu Z, Nellore S, Fane ME, Alicea GM, Weeraratna AT, Simon MC, Singh A, Shaffer SM. Harmange G, et al. Among authors: shaffer sm. Nat Commun. 2024 May 20;15(1):4264. doi: 10.1038/s41467-024-48797-x. Nat Commun. 2024. PMID: 38769307 Free PMC article. No abstract available.
51 results