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Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection.
Allegretti M, Cesta MC, Zippoli M, Beccari A, Talarico C, Mantelli F, Bucci EM, Scorzolini L, Nicastri E. Allegretti M, et al. Among authors: cesta mc. Cell Death Differ. 2022 Jan;29(1):156-166. doi: 10.1038/s41418-021-00844-6. Epub 2021 Aug 17. Cell Death Differ. 2022. PMID: 34404919 Free PMC article. Review.
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.
Bertini R, Allegretti M, Bizzarri C, Moriconi A, Locati M, Zampella G, Cervellera MN, Di Cioccio V, Cesta MC, Galliera E, Martinez FO, Di Bitondo R, Troiani G, Sabbatini V, D'Anniballe G, Anacardio R, Cutrin JC, Cavalieri B, Mainiero F, Strippoli R, Villa P, Di Girolamo M, Martin F, Gentile M, Santoni A, Corda D, Poli G, Mantovani A, Ghezzi P, Colotta F. Bertini R, et al. Among authors: cesta mc. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11791-6. doi: 10.1073/pnas.0402090101. Epub 2004 Jul 28. Proc Natl Acad Sci U S A. 2004. PMID: 15282370 Free PMC article.
Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2.
Moriconi A, Cesta MC, Cervellera MN, Aramini A, Coniglio S, Colagioia S, Beccari AR, Bizzarri C, Cavicchia MR, Locati M, Galliera E, Di Benedetto P, Vigilante P, Bertini R, Allegretti M. Moriconi A, et al. Among authors: cesta mc. J Med Chem. 2007 Aug 23;50(17):3984-4002. doi: 10.1021/jm061469t. Epub 2007 Aug 1. J Med Chem. 2007. PMID: 17665889
Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors.
Sablone MR, Cesta MC, Moriconi A, Aramini A, Bizzarri C, Di Giacinto C, Di Bitondo R, Gloaguen I, Aschi M, Crucianelli M, Bertini R, Allegretti M. Sablone MR, et al. Among authors: cesta mc. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4026-30. doi: 10.1016/j.bmcl.2009.06.027. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19560921
Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor.
Bertini R, Barcelos LS, Beccari AR, Cavalieri B, Moriconi A, Bizzarri C, Di Benedetto P, Di Giacinto C, Gloaguen I, Galliera E, Corsi MM, Russo RC, Andrade SP, Cesta MC, Nano G, Aramini A, Cutrin JC, Locati M, Allegretti M, Teixeira MM. Bertini R, et al. Among authors: cesta mc. Br J Pharmacol. 2012 Jan;165(2):436-54. doi: 10.1111/j.1476-5381.2011.01566.x. Br J Pharmacol. 2012. PMID: 21718305 Free PMC article.
Current status of chemokine receptor inhibitors in development.
Allegretti M, Cesta MC, Garin A, Proudfoot AE. Allegretti M, et al. Among authors: cesta mc. Immunol Lett. 2012 Jul 30;145(1-2):68-78. doi: 10.1016/j.imlet.2012.04.003. Epub 2012 Apr 20. Immunol Lett. 2012. PMID: 22698186 Review.
Allosteric Modulation of Chemoattractant Receptors.
Allegretti M, Cesta MC, Locati M. Allegretti M, et al. Among authors: cesta mc. Front Immunol. 2016 May 2;7:170. doi: 10.3389/fimmu.2016.00170. eCollection 2016. Front Immunol. 2016. PMID: 27199992 Free PMC article. Review.
23 results