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Preclinical evaluation of (S)-[18F]GE387, a novel 18-kDa translocator protein (TSPO) PET radioligand with low binding sensitivity to human polymorphism rs6971.
Ramakrishnan NK, Hird M, Thompson S, Williamson DJ, Qiao L, Owen DR, Brooks AF, Scott PJH, Bacallado S, O'Brien JT, Aigbirhio FI. Ramakrishnan NK, et al. Among authors: williamson dj. Eur J Nucl Med Mol Imaging. 2021 Dec;49(1):125-136. doi: 10.1007/s00259-021-05495-w. Epub 2021 Aug 18. Eur J Nucl Med Mol Imaging. 2021. PMID: 34405276 Free PMC article.
Radiosynthesis of (R,S)-[18 F]GE387: A Potential PET Radiotracer for Imaging Translocator Protein 18 kDa (TSPO) with Low Binding Sensitivity to the Human Gene Polymorphism rs6971.
Qiao L, Fisher E, McMurray L, Milicevic Sephton S, Hird M, Kuzhuppilly-Ramakrishnan N, Williamson DJ, Zhou X, Werry E, Kassiou M, Luthra S, Trigg W, Aigbirhio FI. Qiao L, et al. Among authors: williamson dj. ChemMedChem. 2019 May 6;14(9):982-993. doi: 10.1002/cmdc.201900023. Epub 2019 Apr 8. ChemMedChem. 2019. PMID: 30900397 Free PMC article.
Synthesis and Initial in Vivo Studies with [(11)C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3.
Li L, Shao X, Cole EL, Ohnmacht SA, Ferrari V, Hong YT, Williamson DJ, Fryer TD, Quesada CA, Sherman P, Riss PJ, Scott PJ, Aigbirhio FI. Li L, et al. Among authors: williamson dj. ACS Med Chem Lett. 2015 Mar 10;6(5):548-52. doi: 10.1021/acsmedchemlett.5b00044. eCollection 2015 May 14. ACS Med Chem Lett. 2015. PMID: 26005531 Free PMC article.
167 results