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Hobit identifies tissue-resident memory T cell precursors that are regulated by Eomes.
Parga-Vidal L, Behr FM, Kragten NAM, Nota B, Wesselink TH, Kavazović I, Covill LE, Schuller MBP, Bryceson YT, Wensveen FM, van Lier RAW, van Dam TJP, Stark R, van Gisbergen KPJM. Parga-Vidal L, et al. Among authors: behr fm. Sci Immunol. 2021 Aug 20;6(62):eabg3533. doi: 10.1126/sciimmunol.abg3533. Sci Immunol. 2021. PMID: 34417257
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Mackay LK, Minnich M, Kragten NA, Liao Y, Nota B, Seillet C, Zaid A, Man K, Preston S, Freestone D, Braun A, Wynne-Jones E, Behr FM, Stark R, Pellicci DG, Godfrey DI, Belz GT, Pellegrini M, Gebhardt T, Busslinger M, Shi W, Carbone FR, van Lier RA, Kallies A, van Gisbergen KP. Mackay LK, et al. Among authors: behr fm. Science. 2016 Apr 22;352(6284):459-63. doi: 10.1126/science.aad2035. Science. 2016. PMID: 27102484
Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells.
Kragten NAM, Behr FM, Vieira Braga FA, Remmerswaal EBM, Wesselink TH, Oja AE, Hombrink P, Kallies A, van Lier RAW, Stark R, van Gisbergen KPJM. Kragten NAM, et al. Among authors: behr fm. Eur J Immunol. 2018 Oct;48(10):1644-1662. doi: 10.1002/eji.201847771. Epub 2018 Aug 16. Eur J Immunol. 2018. PMID: 30051906 Free article.
T RM maintenance is regulated by tissue damage via P2RX7.
Stark R, Wesselink TH, Behr FM, Kragten NAM, Arens R, Koch-Nolte F, van Gisbergen KPJM, van Lier RAW. Stark R, et al. Among authors: behr fm. Sci Immunol. 2018 Dec 14;3(30):eaau1022. doi: 10.1126/sciimmunol.aau1022. Sci Immunol. 2018. PMID: 30552101
Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow.
Pascutti MF, Geerman S, Collins N, Brasser G, Nota B, Stark R, Behr F, Oja A, Slot E, Panagioti E, Prier JE, Hickson S, Wolkers MC, Heemskerk MHM, Hombrink P, Arens R, Mackay LK, van Gisbergen KPJM, Nolte MA. Pascutti MF, et al. Eur J Immunol. 2019 Jun;49(6):853-872. doi: 10.1002/eji.201848003. Epub 2019 Apr 2. Eur J Immunol. 2019. PMID: 30891737 Free PMC article.
Murine iNKT cells are depleted by liver damage via activation of P2RX7.
Bovens AA, Wesselink TH, Behr FM, Kragten NAM, van Lier RAW, van Gisbergen KPJM, Stark R. Bovens AA, et al. Among authors: behr fm. Eur J Immunol. 2020 Oct;50(10):1515-1524. doi: 10.1002/eji.201948509. Epub 2020 May 27. Eur J Immunol. 2020. PMID: 32390174 Free article.
18 results