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Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19.
Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar GD, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. Tindle C, et al. Among authors: crotty alexander le. Elife. 2021 Aug 13;10:e66417. doi: 10.7554/eLife.66417. Elife. 2021. PMID: 34463615 Free PMC article.
AI-guided discovery of the invariant host response to viral pandemics.
Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Alexander LEC, Duran J, Crotty S, Dan JM, Das S, Ghosh P. Sahoo D, et al. bioRxiv [Preprint]. 2021 Apr 13:2020.09.21.305698. doi: 10.1101/2020.09.21.305698. bioRxiv. 2021. PMID: 32995790 Free PMC article. Updated. Preprint.
Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19.
Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar G, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. Tindle C, et al. Among authors: crotty alexander le. bioRxiv [Preprint]. 2021 May 5:2020.10.17.344002. doi: 10.1101/2020.10.17.344002. bioRxiv. 2021. PMID: 33106807 Free PMC article. Updated. Preprint.
E-cigarettes compromise the gut barrier and trigger inflammation.
Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF, Ear J, Sahoo D, Crotty-Alexander LE, Ghosh P, Das S. Sharma A, et al. Among authors: crotty alexander le. iScience. 2021 Jan 6;24(2):102035. doi: 10.1016/j.isci.2021.102035. eCollection 2021 Feb 19. iScience. 2021. PMID: 33537654 Free PMC article.
Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients: A Case Series and Review of the Literature.
Masso-Silva JA, Moshensky A, Lam MTY, Odish MF, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott RK, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. Masso-Silva JA, et al. Among authors: crotty s, crotty alexander le, alexander th. Clin Infect Dis. 2022 Feb 11;74(3):479-489. doi: 10.1093/cid/ciab437. Clin Infect Dis. 2022. PMID: 33988226 Free PMC article. Review.
Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity.
Inde Z, Croker BA, Yapp C, Joshi GN, Spetz J, Fraser C, Qin X, Xu L, Deskin B, Ghelfi E, Webb G, Carlin AF, Zhu YP, Leibel SL, Garretson AF, Clark AE, Duran JM, Pretorius V, Crotty-Alexander LE, Li C, Lee JC, Sodhi C, Hackam DJ, Sun X, Hata AN, Kobzik L, Miller J, Park JA, Brownfield D, Jia H, Sarosiek KA. Inde Z, et al. Among authors: crotty alexander le. Sci Adv. 2021 Aug 18;7(34):eabf8609. doi: 10.1126/sciadv.abf8609. Print 2021 Aug. Sci Adv. 2021. PMID: 34407940 Free PMC article.
Inflammatory phenotype modulation in the respiratory tract and systemic circulation of e-cigarette users: a pilot study.
Sayed IM, Masso-Silva JA, Mittal A, Patel A, Lin E, Moshensky A, Shin J, Bojanowski CM, Das S, Akuthota P, Crotty Alexander LE. Sayed IM, et al. Among authors: crotty alexander le. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321(6):L1134-L1146. doi: 10.1152/ajplung.00363.2021. Epub 2021 Oct 27. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34704852 Free PMC article.
Excess neuropeptides in lung signal through endothelial cells to impair gas exchange.
Xu J, Xu L, Sui P, Chen J, Moya EA, Hume P, Janssen WJ, Duran JM, Thistlethwaite P, Carlin A, Gulleman P, Banaschewski B, Goldy MK, Yuan JX, Malhotra A, Pryhuber G, Crotty-Alexander L, Deutsch G, Young LR, Sun X. Xu J, et al. Among authors: crotty alexander l. Dev Cell. 2022 Apr 11;57(7):839-853.e6. doi: 10.1016/j.devcel.2022.02.023. Epub 2022 Mar 17. Dev Cell. 2022. PMID: 35303432 Free PMC article.
Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice.
Moshensky A, Brand CS, Alhaddad H, Shin J, Masso-Silva JA, Advani I, Gunge D, Sharma A, Mehta S, Jahan A, Nilaad S, Olay J, Gu W, Simonson T, Almarghalani D, Pham J, Perera S, Park K, Al-Kolla R, Moon H, Das S, Byun MK, Shah Z, Sari Y, Heller Brown J, Crotty Alexander LE. Moshensky A, et al. Among authors: crotty alexander le. Elife. 2022 Apr 12;11:e67621. doi: 10.7554/eLife.67621. Elife. 2022. PMID: 35411847 Free PMC article.
95 results