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Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.
Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Acín-Pérez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN. Alysandratos KD, et al. Among authors: shirihai os. Cell Rep. 2021 Aug 31;36(9):109636. doi: 10.1016/j.celrep.2021.109636. Cell Rep. 2021. PMID: 34469722 Free PMC article.
Role of mitofusin 2 in the renal stress response.
Gall JM, Wang Z, Liesa M, Molina A, Havasi A, Schwartz JH, Shirihai O, Borkan SC, Bonegio RG. Gall JM, et al. PLoS One. 2012;7(1):e31074. doi: 10.1371/journal.pone.0031074. Epub 2012 Jan 26. PLoS One. 2012. PMID: 22292091 Free PMC article.
Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, Shirihai OS, Chin L, DePinho RA. Hu J, et al. Among authors: shirihai os. Cell. 2012 Feb 17;148(4):651-63. doi: 10.1016/j.cell.2011.12.028. Cell. 2012. PMID: 22341440 Free PMC article.
Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure.
Wikstrom JD, Mahdaviani K, Liesa M, Sereda SB, Si Y, Las G, Twig G, Petrovic N, Zingaretti C, Graham A, Cinti S, Corkey BE, Cannon B, Nedergaard J, Shirihai OS. Wikstrom JD, et al. Among authors: shirihai os. EMBO J. 2014 Mar 3;33(5):418-36. doi: 10.1002/embj.201385014. Epub 2014 Jan 15. EMBO J. 2014. PMID: 24431221 Free PMC article.
Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.
Wilson AA, Ying L, Liesa M, Segeritz CP, Mills JA, Shen SS, Jean J, Lonza GC, Liberti DC, Lang AH, Nazaire J, Gower AC, Müeller FJ, Mehta P, Ordóñez A, Lomas DA, Vallier L, Murphy GJ, Mostoslavsky G, Spira A, Shirihai OS, Ramirez MI, Gadue P, Kotton DN. Wilson AA, et al. Among authors: shirihai os. Stem Cell Reports. 2015 May 12;4(5):873-85. doi: 10.1016/j.stemcr.2015.02.021. Epub 2015 Apr 2. Stem Cell Reports. 2015. PMID: 25843048 Free PMC article.
177 results