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Ruthenium(II) Diphosphine Complexes with Mercapto Ligands That Inhibit Topoisomerase IB and Suppress Tumor Growth In Vivo.
da Silva MM, Ribeiro GH, de Camargo MS, Ferreira AG, Ribeiro L, Barbosa MIF, Deflon VM, Castelli S, Desideri A, Corrêa RS, Ribeiro AB, Nicolella HD, Ozelin SD, Tavares DC, Batista AA. da Silva MM, et al. Among authors: barbosa mif. Inorg Chem. 2021 Sep 20;60(18):14174-14189. doi: 10.1021/acs.inorgchem.1c01539. Epub 2021 Sep 3. Inorg Chem. 2021. PMID: 34477373
Antiparasitic activities of novel ruthenium/lapachol complexes.
Barbosa MI, Corrêa RS, de Oliveira KM, Rodrigues C, Ellena J, Nascimento OR, Rocha VP, Nonato FR, Macedo TS, Barbosa-Filho JM, Soares MB, Batista AA. Barbosa MI, et al. J Inorg Biochem. 2014 Jul;136:33-9. doi: 10.1016/j.jinorgbio.2014.03.009. Epub 2014 Mar 27. J Inorg Biochem. 2014. PMID: 24727183
Study of the cytotoxic and genotoxic potential of the carbonyl ruthenium(II) compound, ct-[RuCl(CO)(dppb)(bipy)]PF6 [dppb = 1,4-bis(diphenylphosphino)butane and bipy = 2,2'-bipyridine], by in vitro and in vivo assays.
Carnizello AP, Alves JM, Pereira DE, Campos JCL, Barbosa MIF, Batista AA, Tavares DC. Carnizello AP, et al. Among authors: barbosa mif. J Appl Toxicol. 2019 Apr;39(4):630-638. doi: 10.1002/jat.3753. Epub 2018 Nov 20. J Appl Toxicol. 2019. PMID: 30460706
[Ru(pipe)(dppb)(bipy)]PF6: A novel ruthenium complex that effectively inhibits ERK activation and cyclin D1 expression in A549 cells.
Ferreira-Silva GA, Ortega MM, Banionis MA, Garavelli GY, Martins FT, Dias JSM, Viegas C Jr, Oliveira JC, Nascimento FBD, Doriguetto AC, Barbosa MIF, Ionta M. Ferreira-Silva GA, et al. Among authors: barbosa mif. Toxicol In Vitro. 2017 Oct;44:382-391. doi: 10.1016/j.tiv.2017.07.019. Epub 2017 Aug 1. Toxicol In Vitro. 2017. PMID: 28774850 Free article.
A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells.
Oliveira MS, Barbosa MIF, de Souza TB, Moreira DRM, Martins FT, Villarreal W, Machado RP, Doriguetto AC, Soares MBP, Bezerra DP. Oliveira MS, et al. Among authors: barbosa mif. Redox Biol. 2019 Jan;20:182-194. doi: 10.1016/j.redox.2018.10.006. Epub 2018 Oct 12. Redox Biol. 2019. PMID: 30359932 Free PMC article.
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