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Ruthenium(II) Diphosphine Complexes with Mercapto Ligands That Inhibit Topoisomerase IB and Suppress Tumor Growth In Vivo.
da Silva MM, Ribeiro GH, de Camargo MS, Ferreira AG, Ribeiro L, Barbosa MIF, Deflon VM, Castelli S, Desideri A, Corrêa RS, Ribeiro AB, Nicolella HD, Ozelin SD, Tavares DC, Batista AA. da Silva MM, et al. Inorg Chem. 2021 Sep 20;60(18):14174-14189. doi: 10.1021/acs.inorgchem.1c01539. Epub 2021 Sep 3. Inorg Chem. 2021. PMID: 34477373
Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death.
Bastos TM, Barbosa MI, da Silva MM, da C Júnior JW, Meira CS, Guimaraes ET, Ellena J, Moreira DR, Batista AA, Soares MB. Bastos TM, et al. Among authors: da silva mm, da c junior jw. Antimicrob Agents Chemother. 2014 Oct;58(10):6044-55. doi: 10.1128/AAC.02765-14. Epub 2014 Aug 4. Antimicrob Agents Chemother. 2014. PMID: 25092707 Free PMC article.
Ruthenium(II) complexes of 1,3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole.
Corrêa RS, da Silva MM, Graminha AE, Meira CS, Santos JA, Moreira DR, Soares MB, Von Poelhsitz G, Castellano EE, Bloch C Jr, Cominetti MR, Batista AA. Corrêa RS, et al. Among authors: da silva mm. J Inorg Biochem. 2016 Mar;156:153-63. doi: 10.1016/j.jinorgbio.2015.12.024. Epub 2016 Jan 2. J Inorg Biochem. 2016. PMID: 26795676
Ru(II)/diphenylphosphine/pyridine-6-thiolate complexes induce S-180 cell apoptosis through intrinsic mitochondrial pathway involving inhibition of Bcl-2 and p53/Bax activation.
Pires WC, Lima BAV, de Castro Pereira F, Lima AP, Mello-Andrade F, Silva HD, da Silva MM, Colina-Vegas L, Ellena J, Batista AA, de Paul Silveira-Lacerda E. Pires WC, et al. Among authors: da silva mm, silva hd. Mol Cell Biochem. 2018 Jan;438(1-2):199-217. doi: 10.1007/s11010-017-3129-3. Epub 2017 Aug 9. Mol Cell Biochem. 2018. PMID: 28795366
Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors.
de Camargo MS, De Grandis RA, da Silva MM, da Silva PB, Santoni MM, Eismann CE, Menegário AA, Cominetti MR, Zanelli CF, Pavan FR, Batista AA. de Camargo MS, et al. Among authors: da silva mm, da silva pb. Biometals. 2019 Feb;32(1):89-100. doi: 10.1007/s10534-018-0160-0. Epub 2018 Nov 30. Biometals. 2019. PMID: 30506342
A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis.
da Silva PB, de Freitas ES, Solcia MC, de Souza PC, da Silva MM, Batista AA, Eismann CE, Rolisola AMCM, Menegário AA, Cardoso RF, Chorilli M, Pavan FR. da Silva PB, et al. Among authors: da silva mm. Front Microbiol. 2018 Dec 6;9:2930. doi: 10.3389/fmicb.2018.02930. eCollection 2018. Front Microbiol. 2018. PMID: 30574128 Free PMC article.
187 results