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A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis.
Absinta M, Maric D, Gharagozloo M, Garton T, Smith MD, Jin J, Fitzgerald KC, Song A, Liu P, Lin JP, Wu T, Johnson KR, McGavern DB, Schafer DP, Calabresi PA, Reich DS. Absinta M, et al. Among authors: gharagozloo m. Nature. 2021 Sep;597(7878):709-714. doi: 10.1038/s41586-021-03892-7. Epub 2021 Sep 8. Nature. 2021. PMID: 34497421 Free PMC article.
NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity.
Gharagozloo M, Mahmoud S, Simard C, Yamamoto K, Bobbala D, Ilangumaran S, Smith MD, Lamontagne A, Jarjoura S, Denault JB, Blais V, Gendron L, Vilariño-Güell C, Sadovnick AD, Ting JP, Calabresi PA, Amrani A, Gris D. Gharagozloo M, et al. PLoS Biol. 2019 Sep 16;17(9):e3000451. doi: 10.1371/journal.pbio.3000451. eCollection 2019 Sep. PLoS Biol. 2019. PMID: 31525189 Free PMC article.
Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation.
Bhargava P, Smith MD, Mische L, Harrington E, Fitzgerald KC, Martin K, Kim S, Reyes AA, Gonzalez-Cardona J, Volsko C, Tripathi A, Singh S, Varanasi K, Lord HN, Meyers K, Taylor M, Gharagozloo M, Sotirchos ES, Nourbakhsh B, Dutta R, Mowry EM, Waubant E, Calabresi PA. Bhargava P, et al. Among authors: gharagozloo m. J Clin Invest. 2020 Jul 1;130(7):3467-3482. doi: 10.1172/JCI129401. J Clin Invest. 2020. PMID: 32182223 Free PMC article.
Complement component 3 from astrocytes mediates retinal ganglion cell loss during neuroinflammation.
Gharagozloo M, Smith MD, Jin J, Garton T, Taylor M, Chao A, Meyers K, Kornberg MD, Zack DJ, Ohayon J, Calabresi BA, Reich DS, Eberhart CG, Pardo CA, Kemper C, Whartenby KA, Calabresi PA. Gharagozloo M, et al. Acta Neuropathol. 2021 Nov;142(5):899-915. doi: 10.1007/s00401-021-02366-4. Epub 2021 Sep 6. Acta Neuropathol. 2021. PMID: 34487221 Free PMC article.
Breaking the barriers to remyelination in multiple sclerosis.
Gharagozloo M, Bannon R, Calabresi PA. Gharagozloo M, et al. Curr Opin Pharmacol. 2022 Apr;63:102194. doi: 10.1016/j.coph.2022.102194. Epub 2022 Mar 4. Curr Opin Pharmacol. 2022. PMID: 35255453 Free PMC article. Review.
Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation.
Smith MD, Chamling X, Gill AJ, Martinez H, Li W, Fitzgerald KC, Sotirchos ES, Moroziewicz D, Bauer L, Paull D, Gharagozloo M, Bhargava P, Zack DJ, Fossati V, Calabresi PA. Smith MD, et al. Among authors: gharagozloo m. Front Mol Neurosci. 2022 May 6;15:874299. doi: 10.3389/fnmol.2022.874299. eCollection 2022. Front Mol Neurosci. 2022. PMID: 35600072 Free PMC article.
The Effects of NLY01, a Novel Glucagon-Like Peptide-1 Receptor Agonist, on Cuprizone-Induced Demyelination and Remyelination: Challenges and Future Perspectives.
Gharagozloo M, Galleguillos D, Jank L, Sotirchos ES, Smith MD, Garton T, Kumar S, Hussein O, Potluri S, Taylor M, Siu C, Mace JW, Dawson T, Dawson VL, Lee S, Calabresi PA. Gharagozloo M, et al. Neurotherapeutics. 2023 Jul;20(4):1229-1240. doi: 10.1007/s13311-023-01390-4. Epub 2023 Jun 9. Neurotherapeutics. 2023. PMID: 37296356 Free article.
73 results