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Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Hotz C, Wagenaar TR, Gieseke F, Bangari DS, Callahan M, Cao H, Diekmann J, Diken M, Grunwitz C, Hebert A, Hsu K, Bernardo M, Karikó K, Kreiter S, Kuhn AN, Levit M, Malkova N, Masciari S, Pollard J, Qu H, Ryan S, Selmi A, Schlereth J, Singh K, Sun F, Tillmann B, Tolstykh T, Weber W, Wicke L, Witzel S, Yu Q, Zhang YA, Zheng G, Lager J, Nabel GJ, Sahin U, Wiederschain D. Hotz C, et al. Among authors: singh k. Sci Transl Med. 2021 Sep 8;13(610):eabc7804. doi: 10.1126/scitranslmed.abc7804. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516826
An experimental model of anti-PD-1 resistance exhibits activation of TGFß and Notch pathways and is sensitive to local mRNA immunotherapy.
Bernardo M, Tolstykh T, Zhang YA, Bangari DS, Cao H, Heyl KA, Lee JS, Malkova NV, Malley K, Marquez E, Pollard J, Qu H, Roberts E, Ryan S, Singh K, Sun F, Wang E, Bahjat K, Wiederschain D, Wagenaar TR. Bernardo M, et al. Among authors: singh k. Oncoimmunology. 2021 Mar 16;10(1):1881268. doi: 10.1080/2162402X.2021.1881268. Oncoimmunology. 2021. PMID: 33796402 Free PMC article.
CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria.
Singh K, Cornell CS, Jackson R, Kabiri M, Phipps M, Desai M, Fogle R, Ying X, Anarat-Cappillino G, Geller S, Johnson J, Roberts E, Malley K, Devlin T, DeRiso M, Berthelette P, Zhang YV, Ryan S, Rao S, Thurberg BL, Bangari DS, Kyostio-Moore S. Singh K, et al. Sci Rep. 2021 Mar 31;11(1):7254. doi: 10.1038/s41598-021-86663-8. Sci Rep. 2021. PMID: 33790381 Free PMC article.
The Novel Phosphate and Bile Acid Sequestrant Polymer SAR442357 Delays Disease Progression in a Rat Model of Diabetic Nephropathy.
Castañeda TR, Méndez M, Davison I, Elvert R, Schwahn U, Boldina G, Rocher C, Scherer P, Singh K, Bangari DS, Falkenhahn M, Kannt A, Konkar A, Larsen PJ, Arbeeny C, Dhal PK, Hübschle T. Castañeda TR, et al. Among authors: singh k. J Pharmacol Exp Ther. 2021 Feb;376(2):190-203. doi: 10.1124/jpet.120.000285. Epub 2020 Nov 17. J Pharmacol Exp Ther. 2021. PMID: 33203659
Tribocorrosion of 3D printed dental implants: An overview.
De Stefano M, Singh K, Raina A, Mohan S, Ul Haq MI, Ruggiero A. De Stefano M, et al. Among authors: singh k. J Taibah Univ Med Sci. 2024 May 12;19(3):644-663. doi: 10.1016/j.jtumed.2024.05.004. eCollection 2024 Jun. J Taibah Univ Med Sci. 2024. PMID: 38807965 Free PMC article. Review.
9,447 results