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Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.
Cho H, Gonzales-Wartz KK, Huang D, Yuan M, Peterson M, Liang J, Beutler N, Torres JL, Cong Y, Postnikova E, Bangaru S, Talana CA, Shi W, Yang ES, Zhang Y, Leung K, Wang L, Peng L, Skinner J, Li S, Wu NC, Liu H, Dacon C, Moyer T, Cohen M, Zhao M, Lee FE, Weinberg RS, Douagi I, Gross R, Schmaljohn C, Pegu A, Mascola JR, Holbrook M, Nemazee D, Rogers TF, Ward AB, Wilson IA, Crompton PD, Tan J. Cho H, et al. Among authors: cohen m. Sci Transl Med. 2021 Oct 20;13(616):eabj5413. doi: 10.1126/scitranslmed.abj5413. Epub 2021 Oct 20. Sci Transl Med. 2021. PMID: 34519517 Free PMC article.
A Phase 2a Randomized, Double-Blind, Dose-Optimizing Study to Evaluate the Immunogenicity and Safety of a Bivalent DNA Vaccine for Hemorrhagic Fever with Renal Syndrome Delivered by Intramuscular Electroporation.
Hooper J, Paolino KM, Mills K, Kwilas S, Josleyn M, Cohen M, Somerville B, Wisniewski M, Norris S, Hill B, Sanchez-Lockhart M, Hannaman D, Schmaljohn CS. Hooper J, et al. Among authors: cohen m. Vaccines (Basel). 2020 Jul 11;8(3):377. doi: 10.3390/vaccines8030377. Vaccines (Basel). 2020. PMID: 32664486 Free PMC article.
Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2.
Hilligan KL, Namasivayam S, Clancy CS, Baker PJ, Old SI, Peluf V, Amaral EP, Oland SD, O'Mard D, Laux J, Cohen M, Garza NL, Lafont BAP, Johnson RF, Feng CG, Jankovic D, Lamiable O, Mayer-Barber KD, Sher A. Hilligan KL, et al. Among authors: cohen m. Nat Commun. 2023 Dec 12;14(1):8229. doi: 10.1038/s41467-023-43447-0. Nat Commun. 2023. PMID: 38086794 Free PMC article.
Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models.
Perley CC, Brocato RL, Wu H, Bausch C, Karmali PP, Vega JB, Cohen MV, Somerville B, Kwilas SA, Principe LM, Shamblin J, Chivukula P, Sullivan E, Hooper JW. Perley CC, et al. Among authors: cohen mv. Front Microbiol. 2020 May 7;11:832. doi: 10.3389/fmicb.2020.00832. eCollection 2020. Front Microbiol. 2020. PMID: 32508764 Free PMC article.
Divergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques.
Wahl-Jensen V, Johnson JC, Lauck M, Weinfurter JT, Moncla LH, Weiler AM, Charlier O, Rojas O, Byrum R, Ragland DR, Huzella L, Zommer E, Cohen M, Bernbaum JG, Caì Y, Sanford HB, Mazur S, Johnson RF, Qin J, Palacios GF, Bailey AL, Jahrling PB, Goldberg TL, O'Connor DH, Friedrich TC, Kuhn JH. Wahl-Jensen V, et al. Among authors: cohen m. mBio. 2016 Feb 23;7(1):e02009-15. doi: 10.1128/mBio.02009-15. mBio. 2016. PMID: 26908578 Free PMC article.
Cytoprotective 3K3A-activated protein C and plasma: A comparison of therapeutics for the endotheliopathy of trauma.
Thielen O, Stafford P, Debot M, Kelher M, Mitra S, Hallas W, Gallagher LT, Schaid T, Stocker B, Ramser B, D'Alessandro A, Hansen K, Silliman CC, Moore E, Mosnier L, Griffin J, Cohen M. Thielen O, et al. Among authors: cohen m. J Trauma Acute Care Surg. 2024 May 27. doi: 10.1097/TA.0000000000004406. Online ahead of print. J Trauma Acute Care Surg. 2024. PMID: 38797883
Impact of LS Mutation on Pharmacokinetics of Preventive HIV Broadly Neutralizing Monoclonal Antibodies: A Cross-Protocol Analysis of 16 Clinical Trials in People without HIV.
Mayer BT, Zhang L, deCamp AC, Yu C, Sato A, Angier H, Seaton KE, Yates N, Ledgerwood JE, Mayer K, Caskey M, Nussenzweig M, Stephenson K, Julg B, Barouch DH, Sobieszczyk ME, Edupuganti S, Kelley CF, McElrath MJ, Gelderblom HC, Pensiero M, McDermott A, Gama L, Koup RA, Gilbert PB, Cohen MS, Corey L, Hyrien O, Tomaras GD, Huang Y. Mayer BT, et al. Among authors: cohen ms. Pharmaceutics. 2024 Apr 27;16(5):594. doi: 10.3390/pharmaceutics16050594. Pharmaceutics. 2024. PMID: 38794258 Free PMC article.
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