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A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses.
Beumer J, Geurts MH, Lamers MM, Puschhof J, Zhang J, van der Vaart J, Mykytyn AZ, Breugem TI, Riesebosch S, Schipper D, van den Doel PB, de Lau W, Pleguezuelos-Manzano C, Busslinger G, Haagmans BL, Clevers H. Beumer J, et al. Among authors: busslinger g. Nat Commun. 2021 Sep 17;12(1):5498. doi: 10.1038/s41467-021-25729-7. Nat Commun. 2021. PMID: 34535662 Free PMC article.
High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells.
Beumer J, Puschhof J, Bauzá-Martinez J, Martínez-Silgado A, Elmentaite R, James KR, Ross A, Hendriks D, Artegiani B, Busslinger GA, Ponsioen B, Andersson-Rolf A, Saftien A, Boot C, Kretzschmar K, Geurts MH, Bar-Ephraim YE, Pleguezuelos-Manzano C, Post Y, Begthel H, van der Linden F, Lopez-Iglesias C, van de Wetering WJ, van der Linden R, Peters PJ, Heck AJR, Goedhart J, Snippert H, Zilbauer M, Teichmann SA, Wu W, Clevers H. Beumer J, et al. Cell. 2020 Jun 11;181(6):1291-1306.e19. doi: 10.1016/j.cell.2020.04.036. Epub 2020 May 13. Cell. 2020. PMID: 32407674 Free article.
High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells.
Beumer J, Puschhof J, Bauzá-Martinez J, Martínez-Silgado A, Elmentaite R, James KR, Ross A, Hendriks D, Artegiani B, Busslinger GA, Ponsioen B, Andersson-Rolf A, Saftien A, Boot C, Kretzschmar K, Geurts MH, Bar-Ephraim YE, Pleguezuelos-Manzano C, Post Y, Begthel H, van der Linden F, Lopez-Iglesias C, van de Wetering WJ, van der Linden R, Peters PJ, Heck AJR, Goedhart J, Snippert H, Zilbauer M, Teichmann SA, Wu W, Clevers H. Beumer J, et al. Cell. 2020 Aug 20;182(4):1062-1064. doi: 10.1016/j.cell.2020.08.005. Cell. 2020. PMID: 32822568 Free article. No abstract available.
SARS-CoV-2 infection and replication in human gastric organoids.
Giobbe GG, Bonfante F, Jones BC, Gagliano O, Luni C, Zambaiti E, Perin S, Laterza C, Busslinger G, Stuart H, Pagliari M, Bortolami A, Mazzetto E, Manfredi A, Colantuono C, Di Filippo L, Pellegata AF, Panzarin V, Thapar N, Li VSW, Eaton S, Cacchiarelli D, Clevers H, Elvassore N, De Coppi P. Giobbe GG, et al. Among authors: busslinger g. Nat Commun. 2021 Nov 16;12(1):6610. doi: 10.1038/s41467-021-26762-2. Nat Commun. 2021. PMID: 34785679 Free PMC article.
Molecular characterization of Barrett's esophagus at single-cell resolution.
Busslinger GA, de Barbanson B, Oka R, Weusten BLA, de Maat M, van Hillegersberg R, Brosens LAA, van Boxtel R, van Oudenaarden A, Clevers H. Busslinger GA, et al. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2113061118. doi: 10.1073/pnas.2113061118. Proc Natl Acad Sci U S A. 2021. PMID: 34795059 Free PMC article.
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