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Lrp1 is a host entry factor for Rift Valley fever virus.
Ganaie SS, Schwarz MM, McMillen CM, Price DA, Feng AX, Albe JR, Wang W, Miersch S, Orvedahl A, Cole AR, Sentmanat MF, Mishra N, Boyles DA, Koenig ZT, Kujawa MR, Demers MA, Hoehl RM, Moyle AB, Wagner ND, Stubbs SH, Cardarelli L, Teyra J, McElroy A, Gross ML, Whelan SPJ, Doench J, Cui X, Brett TJ, Sidhu SS, Virgin HW, Egawa T, Leung DW, Amarasinghe GK, Hartman AL. Ganaie SS, et al. Cell. 2021 Sep 30;184(20):5163-5178.e24. doi: 10.1016/j.cell.2021.09.001. Epub 2021 Sep 23. Cell. 2021. PMID: 34559985 Free PMC article.
Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
Miersch S, Li Z, Saberianfar R, Ustav M, Case JB, Blazer L, Chen C, Ye W, Pavlenco A, Gorelik M, Perez JG, Subramania S, Singh S, Ploder L, Ganaie S, Chen RE, Leung DW, Pandolfi PP, Novelli G, Matusali G, Colavita F, Capobianchi MR, Jain S, Gupta JB, Amarasinghe GK, Diamond MS, Rini J, Sidhu SS. Miersch S, et al. Among authors: ganaie s. bioRxiv [Preprint]. 2020 Dec 21:2020.10.31.362848. doi: 10.1101/2020.10.31.362848. bioRxiv. 2020. PMID: 33398270 Free PMC article. Updated. Preprint.
Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
Miersch S, Li Z, Saberianfar R, Ustav M, Brett Case J, Blazer L, Chen C, Ye W, Pavlenco A, Gorelik M, Garcia Perez J, Subramania S, Singh S, Ploder L, Ganaie S, Chen RE, Leung DW, Pandolfi PP, Novelli G, Matusali G, Colavita F, Capobianchi MR, Jain S, Gupta JB, Amarasinghe GK, Diamond MS, Rini J, Sidhu SS. Miersch S, et al. Among authors: ganaie s. J Mol Biol. 2021 Sep 17;433(19):167177. doi: 10.1016/j.jmb.2021.167177. Epub 2021 Jul 28. J Mol Biol. 2021. PMID: 34329642 Free PMC article.
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1.
Schwarz MM, Price DA, Ganaie SS, Feng A, Mishra N, Hoehl RM, Fatma F, Stubbs SH, Whelan SPJ, Cui X, Egawa T, Leung DW, Amarasinghe GK, Hartman AL. Schwarz MM, et al. Among authors: ganaie ss. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2204706119. doi: 10.1073/pnas.2204706119. Epub 2022 Aug 8. Proc Natl Acad Sci U S A. 2022. PMID: 35939689 Free PMC article.
Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.
van Vliet VJE, Huynh N, Palà J, Patel A, Singer A, Slater C, Chung J, van Huizen M, Teyra J, Miersch S, Luu GK, Ye W, Sharma N, Ganaie SS, Russell R, Chen C, Maynard M, Amarasinghe GK, Mark BL, Kikkert M, Sidhu SS. van Vliet VJE, et al. Among authors: ganaie ss. PLoS Pathog. 2022 Dec 22;18(12):e1011065. doi: 10.1371/journal.ppat.1011065. eCollection 2022 Dec. PLoS Pathog. 2022. PMID: 36548304 Free PMC article.
Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice.
Schwarz MM, Ganaie SS, Feng A, Brown G, Yangdon T, White JM, Hoehl RM, McMillen CM, Rush RE, Connors KA, Cui X, Leung DW, Egawa T, Amarasinghe GK, Hartman AL. Schwarz MM, et al. Among authors: ganaie ss. Sci Adv. 2023 Jul 14;9(28):eadh2264. doi: 10.1126/sciadv.adh2264. Epub 2023 Jul 14. Sci Adv. 2023. PMID: 37450601 Free PMC article.
27 results