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Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury.
Graham NSN, Zimmerman KA, Moro F, Heslegrave A, Maillard SA, Bernini A, Miroz JP, Donat CK, Lopez MY, Bourke N, Jolly AE, Mallas EJ, Soreq E, Wilson MH, Fatania G, Roi D, Patel MC, Garbero E, Nattino G, Baciu C, Fainardi E, Chieregato A, Gradisek P, Magnoni S, Oddo M, Zetterberg H, Bertolini G, Sharp DJ. Graham NSN, et al. Among authors: heslegrave a. Sci Transl Med. 2021 Sep 29;13(613):eabg9922. doi: 10.1126/scitranslmed.abg9922. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586833
Plasma tau is increased in frontotemporal dementia.
Foiani MS, Woollacott IO, Heller C, Bocchetta M, Heslegrave A, Dick KM, Russell LL, Marshall CR, Mead S, Schott JM, Fox NC, Warren JD, Zetterberg H, Rohrer JD. Foiani MS, et al. Among authors: heslegrave a. J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):804-807. doi: 10.1136/jnnp-2017-317260. Epub 2018 Feb 13. J Neurol Neurosurg Psychiatry. 2018. PMID: 29440230 Free PMC article.
Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression.
Thompson AGB, Luk C, Heslegrave AJ, Zetterberg H, Mead SH, Collinge J, Jackson GS. Thompson AGB, et al. J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):955-961. doi: 10.1136/jnnp-2017-317793. Epub 2018 Feb 27. J Neurol Neurosurg Psychiatry. 2018. PMID: 29487167 Free PMC article.
Cerebrospinal fluid neurogranin and TREM2 in Huntington's disease.
Byrne LM, Rodrigues FB, Johnson EB, De Vita E, Blennow K, Scahill R, Zetterberg H, Heslegrave A, Wild EJ. Byrne LM, et al. Among authors: heslegrave a. Sci Rep. 2018 Mar 9;8(1):4260. doi: 10.1038/s41598-018-21788-x. Sci Rep. 2018. PMID: 29523800 Free PMC article. Clinical Trial.
Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic.
Paterson RW, Slattery CF, Poole T, Nicholas JM, Magdalinou NK, Toombs J, Chapman MD, Lunn MP, Heslegrave AJ, Foiani MS, Weston PSJ, Keshavan A, Rohrer JD, Rossor MN, Warren JD, Mummery CJ, Blennow K, Fox NC, Zetterberg H, Schott JM. Paterson RW, et al. Among authors: heslegrave aj. Alzheimers Res Ther. 2018 Mar 20;10(1):32. doi: 10.1186/s13195-018-0361-3. Alzheimers Res Ther. 2018. PMID: 29558979 Free PMC article.
149 results