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Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension.
Toshner M, Church C, Harbaum L, Rhodes C, Villar Moreschi SS, Liley J, Jones R, Arora A, Batai K, Desai AA, Coghlan JG, Gibbs JSR, Gor D, Gräf S, Harlow L, Hernandez-Sanchez J, Howard LS, Humbert M, Karnes J, Kiely DG, Kittles R, Knightbridge E, Lam B, Lutz KA, Nichols WC, Pauciulo MW, Pepke-Zaba J, Suntharalingam J, Soubrier F, Trembath RC, Schwantes-An TL, Wort SJ, Wilkins MR, Gaine S, Morrell NW, Corris PA; Uniphy Clinical Trials Network. Toshner M, et al. Among authors: schwantes an tl. Eur Respir J. 2022 Mar 10;59(3):2002463. doi: 10.1183/13993003.02463-2020. Print 2022 Mar. Eur Respir J. 2022. PMID: 34588193 Free PMC article.
RASA3 is a candidate gene in sickle cell disease-associated pulmonary hypertension and pulmonary arterial hypertension.
Prohaska CC, Zhang X, Schwantes-An TL, Stearman RS, Hooker S, Kittles RA, Aldred MA, Lutz KA, Pauciulo MW, Nichols WC, Desai AA, Gordeuk VR, Machado RF. Prohaska CC, et al. Among authors: schwantes an tl. Pulm Circ. 2023 Apr 1;13(2):e12227. doi: 10.1002/pul2.12227. eCollection 2023 Apr. Pulm Circ. 2023. PMID: 37101805 Free PMC article.
Genetic associations with childhood brain growth, defined in two longitudinal cohorts.
Szekely E, Schwantes-An TL, Justice CM, Sabourin JA, Jansen PR, Muetzel RL, Sharp W, Tiemeier H, Sung H, White TJ, Wilson AF, Shaw P. Szekely E, et al. Among authors: schwantes an tl. Genet Epidemiol. 2018 Jun;42(4):405-414. doi: 10.1002/gepi.22122. Epub 2018 Apr 22. Genet Epidemiol. 2018. PMID: 29682794 Free PMC article.
Characterization of a novel deep-intronic variant in DYNC2H1 identified by whole-exome sequencing in a patient with a lethal form of a short-rib thoracic dysplasia type III.
Buchh M, Gillespie PJ, Treat K, Abreu MA, Schwantes-An TL, Helm BM, Fang F, Xuei X, Mantcheva L, Suhrie KR, Graham BH, Conboy E, Vetrini F. Buchh M, et al. Among authors: schwantes an tl. Cold Spring Harb Mol Case Stud. 2022 Dec 28;8(7):a006254. doi: 10.1101/mcs.a006254. Print 2022 Dec. Cold Spring Harb Mol Case Stud. 2022. PMID: 36442996 Free PMC article.