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Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections.
Heemskerk MT, Korbee CJ, Esselink JJ, Dos Santos CC, van Veen S, Gordijn IF, Vrieling F, Walburg KV, Engele CG, Dijkman K, Wilson L, Verreck FAW, Ottenhoff THM, Haks MC. Heemskerk MT, et al. Among authors: haks mc. Sci Rep. 2021 Oct 4;11(1):19634. doi: 10.1038/s41598-021-98980-z. Sci Rep. 2021. PMID: 34608194 Free PMC article.
Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability.
Huttner A, Agnandji ST, Engler O, Hooper JW, Kwilas S, Ricks K, Clements TL, Jonsdottir HR, Nakka SS, Rothenberger S, Kremsner P, Züst R, Medaglini D, Ottenhoff T, Harandi AM, Siegrist CA; VEBCON; VSV-EBOVAC; VSV-EBOPLUS Consortia. Huttner A, et al. Clin Microbiol Infect. 2023 Dec;29(12):1587-1594. doi: 10.1016/j.cmi.2023.08.026. Epub 2023 Sep 3. Clin Microbiol Infect. 2023. PMID: 37661067
Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity.
Sutherland JS, Loxton AG, Haks MC, Kassa D, Ambrose L, Lee JS, Ran L, van Baarle D, Maertzdorf J, Howe R, Mayanja-Kizza H, Boom WH, Thiel BA, Crampin AC, Hanekom W, Ota MO, Dockrell H, Walzl G, Kaufmann SH, Ottenhoff TH; GCGH Biomarkers for TB consortium. Sutherland JS, et al. Among authors: haks mc. Clin Microbiol Infect. 2014 Apr;20(4):O230-8. doi: 10.1111/1469-0691.12383. Epub 2013 Nov 11. Clin Microbiol Infect. 2014. PMID: 24205913 Free article.
Global blood miRNA profiling unravels early signatures of immunogenicity of Ebola vaccine rVSVΔG-ZEBOV-GP.
Vianello E, Persson J, Andersson B, van Veen S, Dias TL, Santoro F, Östensson M, Obudulu O, Agbajogu C, Torkzadeh S; VSV-EBOVAC; VSV-EBOPLUS Consortia; Nakaya HI, Medaglini D, Siegrist CA, Ottenhoff THM, Harandi AM. Vianello E, et al. iScience. 2023 Nov 23;26(12):108574. doi: 10.1016/j.isci.2023.108574. eCollection 2023 Dec 15. iScience. 2023. PMID: 38162033 Free PMC article.
Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts.
Gonzalez Dias Carvalho PC, Dominguez Crespo Hirata T, Mano Alves LY, Moscardini IF, do Nascimento APB, Costa-Martins AG, Sorgi S, Harandi AM, Ferreira DM, Vianello E, Haks MC, Ottenhoff THM, Santoro F, Martinez-Murillo P, Huttner A, Siegrist CA, Medaglini D, Nakaya HI. Gonzalez Dias Carvalho PC, et al. Among authors: haks mc. Front Immunol. 2023 Nov 8;14:1259197. doi: 10.3389/fimmu.2023.1259197. eCollection 2023. Front Immunol. 2023. PMID: 38022684 Free PMC article.
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity.
Eckold C, van Doorn CLR, Ruslami R, Ronacher K, Riza AL, van Veen S, Lee JS, Kumar V, Kerry-Barnard S, Malherbe ST, Kleynhans L, Stanley K, Joosten SA, Critchley JA, Hill PC, van Crevel R, Wijmenga C, Haks MC, Ioana M, Alisjahbana B, Walzl G, Ottenhoff THM, Dockrell HM, Vianello E, Cliff JM; TANDEM Consortium$. Eckold C, et al. Among authors: haks mc. Clin Transl Med. 2023 Sep;13(9):e1375. doi: 10.1002/ctm2.1375. Clin Transl Med. 2023. PMID: 37649224 Free PMC article.
T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection.
Musvosvi M, Huang H, Wang C, Xia Q, Rozot V, Krishnan A, Acs P, Cheruku A, Obermoser G, Leslie A, Behar SM, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Walzl G, Hatherill M, Davis MM, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium. Musvosvi M, et al. Nat Med. 2023 Jan;29(1):258-269. doi: 10.1038/s41591-022-02110-9. Epub 2023 Jan 5. Nat Med. 2023. PMID: 36604540 Free PMC article.
Repurposing Tamoxifen as Potential Host-Directed Therapeutic for Tuberculosis.
Boland R, Heemskerk MT, Forn-Cuní G, Korbee CJ, Walburg KV, Esselink JJ, Carvalho Dos Santos C, de Waal AM, van der Hoeven DCM, van der Sar E, de Ries AS, Xie J, Spaink HP, van der Vaart M, Haks MC, Meijer AH, Ottenhoff THM. Boland R, et al. Among authors: haks mc. mBio. 2023 Feb 28;14(1):e0302422. doi: 10.1128/mbio.03024-22. Epub 2022 Dec 7. mBio. 2023. PMID: 36475748 Free PMC article.
81 results