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Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce.
Li Q, Hagberg CE, Silva Cascales H, Lang S, Hyvönen MT, Salehzadeh F, Chen P, Alexandersson I, Terezaki E, Harms MJ, Kutschke M, Arifen N, Krämer N, Aouadi M, Knibbe C, Boucher J, Thorell A, Spalding KL. Li Q, et al. Among authors: hyvonen mt. Nat Med. 2021 Nov;27(11):1941-1953. doi: 10.1038/s41591-021-01501-8. Epub 2021 Oct 4. Nat Med. 2021. PMID: 34608330
Maintenance of white adipose tissue in man.
Hyvönen MT, Spalding KL. Hyvönen MT, et al. Int J Biochem Cell Biol. 2014 Nov;56:123-32. doi: 10.1016/j.biocel.2014.09.013. Epub 2014 Sep 20. Int J Biochem Cell Biol. 2014. PMID: 25240584 Review.
Chemical activation of SAT1 corrects diet-induced metabolic syndrome.
Castoldi F, Hyvönen MT, Durand S, Aprahamian F, Sauvat A, Malik SA, Baracco EE, Vacchelli E, Opolon P, Signolle N, Lefevre D, Bossut N, Eisenberg T, Dammbrueck C, Pendl T, Kremer M, Lachkar S, Einer C, Michalke B, Zischka H, Madeo F, Keinänen TA, Maiuri MC, Pietrocola F, Kroemer G. Castoldi F, et al. Among authors: hyvonen mt. Cell Death Differ. 2020 Oct;27(10):2904-2920. doi: 10.1038/s41418-020-0550-z. Epub 2020 May 6. Cell Death Differ. 2020. PMID: 32376874 Free PMC article.
Charge deficient analogues of the natural polyamines.
Weisell J, Hyvönen MT, Alhonen L, Vepsäläinen J, Keinänen TA, Khomutov AR. Weisell J, et al. Among authors: hyvonen mt. Curr Pharm Des. 2014;20(2):262-77. doi: 10.2174/13816128113199990037. Curr Pharm Des. 2014. PMID: 23701551 Review.
Complex N-acetylation of triethylenetetramine.
Cerrada-Gimenez M, Weisell J, Hyvönen MT, Park MH, Alhonen L, Vepsäläinen J, Keinänen TA. Cerrada-Gimenez M, et al. Among authors: hyvonen mt. Drug Metab Dispos. 2011 Dec;39(12):2242-9. doi: 10.1124/dmd.111.041798. Epub 2011 Aug 30. Drug Metab Dispos. 2011. PMID: 21878558 Free PMC article.
75 results