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Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce.
Li Q, Hagberg CE, Silva Cascales H, Lang S, Hyvönen MT, Salehzadeh F, Chen P, Alexandersson I, Terezaki E, Harms MJ, Kutschke M, Arifen N, Krämer N, Aouadi M, Knibbe C, Boucher J, Thorell A, Spalding KL. Li Q, et al. Nat Med. 2021 Nov;27(11):1941-1953. doi: 10.1038/s41591-021-01501-8. Epub 2021 Oct 4. Nat Med. 2021. PMID: 34608330
Cellular senescence and its role in white adipose tissue.
Smith U, Li Q, Rydén M, Spalding KL. Smith U, et al. Among authors: li q. Int J Obes (Lond). 2021 May;45(5):934-943. doi: 10.1038/s41366-021-00757-x. Epub 2021 Jan 28. Int J Obes (Lond). 2021. PMID: 33510393 Review.
Transforming Growth Factor-β3 Regulates Adipocyte Number in Subcutaneous White Adipose Tissue.
Petrus P, Mejhert N, Corrales P, Lecoutre S, Li Q, Maldonado E, Kulyté A, Lopez Y, Campbell M, Acosta JR, Laurencikiene J, Douagi I, Gao H, Martínez-Álvarez C, Hedén P, Spalding KL, Vidal-Puig A, Medina-Gomez G, Arner P, Rydén M. Petrus P, et al. Among authors: li q. Cell Rep. 2018 Oct 16;25(3):551-560.e5. doi: 10.1016/j.celrep.2018.09.069. Cell Rep. 2018. PMID: 30332637 Free article.
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