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Engineering living therapeutics with synthetic biology.
Cubillos-Ruiz A, Guo T, Sokolovska A, Miller PF, Collins JJ, Lu TK, Lora JM. Cubillos-Ruiz A, et al. Among authors: lora jm. Nat Rev Drug Discov. 2021 Dec;20(12):941-960. doi: 10.1038/s41573-021-00285-3. Epub 2021 Oct 6. Nat Rev Drug Discov. 2021. PMID: 34616030 Review.
Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.
Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernández LÁ, Lora JM, Kaufman HL, Quintana FJ, Geiger R, F Lesser C, Lynch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, De Coster T, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW. Cable J, et al. Among authors: lora jm. Ann N Y Acad Sci. 2021 Dec;1506(1):98-117. doi: 10.1111/nyas.14710. Epub 2021 Nov 16. Ann N Y Acad Sci. 2021. PMID: 34786712 Review.
Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity.
Leventhal DS, Sokolovska A, Li N, Plescia C, Kolodziej SA, Gallant CW, Christmas R, Gao JR, James MJ, Abin-Fuentes A, Momin M, Bergeron C, Fisher A, Miller PF, West KA, Lora JM. Leventhal DS, et al. Among authors: lora jm. Nat Commun. 2020 Jun 1;11(1):2739. doi: 10.1038/s41467-020-16602-0. Nat Commun. 2020. PMID: 32483165 Free PMC article.
Metabolic modulation of tumours with engineered bacteria for immunotherapy.
Canale FP, Basso C, Antonini G, Perotti M, Li N, Sokolovska A, Neumann J, James MJ, Geiger S, Jin W, Theurillat JP, West KA, Leventhal DS, Lora JM, Sallusto F, Geiger R. Canale FP, et al. Among authors: lora jm. Nature. 2021 Oct;598(7882):662-666. doi: 10.1038/s41586-021-04003-2. Epub 2021 Oct 6. Nature. 2021. PMID: 34616044
Suppression of inflammation by a synthetic histone mimic.
Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung CW, Chandwani R, Marazzi I, Wilson P, Coste H, White J, Kirilovsky J, Rice CM, Lora JM, Prinjha RK, Lee K, Tarakhovsky A. Nicodeme E, et al. Among authors: lora jm. Nature. 2010 Dec 23;468(7327):1119-23. doi: 10.1038/nature09589. Epub 2010 Nov 10. Nature. 2010. PMID: 21068722 Free PMC article.
Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis.
Gonzalo JA, Qiu Y, Lora JM, Al-Garawi A, Villeval JL, Boyce JA, Martinez-A C, Marquez G, Goya I, Hamid Q, Fraser CC, Picarella D, Cote-Sierra J, Hodge MR, Gutierrez-Ramos JC, Kolbeck R, Coyle AJ. Gonzalo JA, et al. Among authors: lora jm. J Immunol. 2007 Aug 1;179(3):1740-50. doi: 10.4049/jimmunol.179.3.1740. J Immunol. 2007. PMID: 17641040
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