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Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis.
Pernigoni N, Zagato E, Calcinotto A, Troiani M, Mestre RP, Calì B, Attanasio G, Troisi J, Minini M, Mosole S, Revandkar A, Pasquini E, Elia AR, Bossi D, Rinaldi A, Rescigno P, Flohr P, Hunt J, Neeb A, Buroni L, Guo C, Welti J, Ferrari M, Grioni M, Gauthier J, Gharaibeh RZ, Palmisano A, Lucchini GM, D'Antonio E, Merler S, Bolis M, Grassi F, Esposito A, Bellone M, Briganti A, Rescigno M, Theurillat JP, Jobin C, Gillessen S, de Bono J, Alimonti A. Pernigoni N, et al. Among authors: bolis m. Science. 2021 Oct 8;374(6564):216-224. doi: 10.1126/science.abf8403. Epub 2021 Oct 7. Science. 2021. PMID: 34618582
CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo.
Alajati A, D'Ambrosio M, Troiani M, Mosole S, Pellegrini L, Chen J, Revandkar A, Bolis M, Theurillat JP, Guccini I, Losa M, Calcinotto A, De Bernardis G, Pasquini E, D'Antuono R, Sharp A, Figueiredo I, Nava Rodrigues D, Welti J, Gil V, Yuan W, Vlajnic T, Bubendorf L, Chiorino G, Gnetti L, Torrano V, Carracedo A, Camplese L, Hirabayashi S, Canato E, Pasut G, Montopoli M, Rüschoff JH, Wild P, Moch H, De Bono J, Alimonti A. Alajati A, et al. Among authors: bolis m. J Clin Invest. 2020 May 1;130(5):2435-2450. doi: 10.1172/JCI131133. J Clin Invest. 2020. PMID: 32250342 Free PMC article.
Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ.
Paroni G, Zanetti A, Barzago MM, Kurosaki M, Guarrera L, Fratelli M, Troiani M, Ubezio P, Bolis M, Vallerga A, Biancardi F, Terao M, Garattini E. Paroni G, et al. Among authors: bolis m. Cancers (Basel). 2020 Oct 18;12(10):3027. doi: 10.3390/cancers12103027. Cancers (Basel). 2020. PMID: 33081033 Free PMC article.
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.
Bernasocchi T, El Tekle G, Bolis M, Mutti A, Vallerga A, Brandt LP, Spriano F, Svinkina T, Zoma M, Ceserani V, Rinaldi A, Janouskova H, Bossi D, Cavalli M, Mosole S, Geiger R, Dong Z, Yang CG, Albino D, Rinaldi A, Schraml P, Linder S, Carbone GM, Alimonti A, Bertoni F, Moch H, Carr SA, Zwart W, Kruithof-de Julio M, Rubin MA, Udeshi ND, Theurillat JP. Bernasocchi T, et al. Among authors: bolis m. Nat Commun. 2021 Feb 2;12(1):734. doi: 10.1038/s41467-020-20820-x. Nat Commun. 2021. PMID: 33531470 Free PMC article.
Patient-derived xenografts and organoids model therapy response in prostate cancer.
Karkampouna S, La Manna F, Benjak A, Kiener M, De Menna M, Zoni E, Grosjean J, Klima I, Garofoli A, Bolis M, Vallerga A, Theurillat JP, De Filippo MR, Genitsch V, Keller D, Booij TH, Stirnimann CU, Eng K, Sboner A, Ng CKY, Piscuoglio S, Gray PC, Spahn M, Rubin MA, Thalmann GN, Kruithof-de Julio M. Karkampouna S, et al. Among authors: bolis m. Nat Commun. 2021 Feb 18;12(1):1117. doi: 10.1038/s41467-021-21300-6. Nat Commun. 2021. PMID: 33602919 Free PMC article.
Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression.
Bolis M, Bossi D, Vallerga A, Ceserani V, Cavalli M, Impellizzieri D, Di Rito L, Zoni E, Mosole S, Elia AR, Rinaldi A, Pereira Mestre R, D'Antonio E, Ferrari M, Stoffel F, Jermini F, Gillessen S, Bubendorf L, Schraml P, Calcinotto A, Corey E, Moch H, Spahn M, Thalmann G, Kruithof-de Julio M, Rubin MA, Theurillat JP. Bolis M, et al. Nat Commun. 2021 Dec 2;12(1):7033. doi: 10.1038/s41467-021-26840-5. Nat Commun. 2021. PMID: 34857732 Free PMC article.
Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.
Troiani M, Colucci M, D'Ambrosio M, Guccini I, Pasquini E, Varesi A, Valdata A, Mosole S, Revandkar A, Attanasio G, Rinaldi A, Rinaldi A, Bolis M, Cippà P, Alimonti A. Troiani M, et al. Among authors: bolis m. Nat Commun. 2022 Apr 21;13(1):2177. doi: 10.1038/s41467-022-29824-1. Nat Commun. 2022. PMID: 35449130 Free PMC article.
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer.
Bancaro N, Calì B, Troiani M, Elia AR, Arzola RA, Attanasio G, Lai P, Crespo M, Gurel B, Pereira R, Guo C, Mosole S, Brina D, D'Ambrosio M, Pasquini E, Spataro C, Zagato E, Rinaldi A, Pedotti M, Di Lascio S, Meani F, Montopoli M, Ferrari M, Gallina A, Varani L, Pereira Mestre R, Bolis M, Gillessen Sommer S, de Bono J, Calcinotto A, Alimonti A. Bancaro N, et al. Among authors: bolis m. Cancer Cell. 2023 Mar 13;41(3):602-619.e11. doi: 10.1016/j.ccell.2023.02.004. Epub 2023 Mar 2. Cancer Cell. 2023. PMID: 36868226 Free article.
75 results