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Phase 1/2a, open-label, multicenter study of RM-1929 photoimmunotherapy in patients with locoregional, recurrent head and neck squamous cell carcinoma.
Cognetti DM, Johnson JM, Curry JM, Kochuparambil ST, McDonald D, Mott F, Fidler MJ, Stenson K, Vasan NR, Razaq MA, Campana J, Ha P, Mann G, Ishida K, Garcia-Guzman M, Biel M, Gillenwater AM. Cognetti DM, et al. Among authors: garcia guzman m. Head Neck. 2021 Dec;43(12):3875-3887. doi: 10.1002/hed.26885. Epub 2021 Oct 9. Head Neck. 2021. PMID: 34626024 Free PMC article. Clinical Trial.
Near infra-red photoimmunotherapy with anti-CEA-IR700 results in extensive tumor lysis and a significant decrease in tumor burden in orthotopic mouse models of pancreatic cancer.
Maawy AA, Hiroshima Y, Zhang Y, Heim R, Makings L, Garcia-Guzman M, Luiken GA, Kobayashi H, Hoffman RM, Bouvet M. Maawy AA, et al. Among authors: garcia guzman m. PLoS One. 2015 Mar 23;10(3):e0121989. doi: 10.1371/journal.pone.0121989. eCollection 2015. PLoS One. 2015. PMID: 25799218 Free PMC article.
Cancer-targeted photoimmunotherapy induces antitumor immunity and can be augmented by anti-PD-1 therapy for durable anticancer responses in an immunologically active murine tumor model.
Hsu MA, Okamura SM, De Magalhaes Filho CD, Bergeron DM, Rodriguez A, West M, Yadav D, Heim R, Fong JJ, Garcia-Guzman M. Hsu MA, et al. Among authors: garcia guzman m. Cancer Immunol Immunother. 2023 Jan;72(1):151-168. doi: 10.1007/s00262-022-03239-9. Epub 2022 Jul 1. Cancer Immunol Immunother. 2023. PMID: 35776159 Free PMC article.
Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis.
Migliore M Dr, Pontis S Dr, Fuentes de Arriba AL, Realini N, Torrente E, Armirotti A, Romeo E, Di Martino S, Russo D, Pizzirani D, Summa M, Lanfranco M, Ottonello G, Busquet P, Jung KM, Garcia-Guzman M, Heim R, Scarpelli R, Piomelli D. Migliore M Dr, et al. Among authors: garcia guzman m. Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11193-11197. doi: 10.1002/anie.201603746. Epub 2016 Jul 12. Angew Chem Int Ed Engl. 2016. PMID: 27404798 Free PMC article.
33 results