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Replication and single-cycle delivery of SARS-CoV-2 replicons.
Ricardo-Lax I, Luna JM, Thao TTN, Le Pen J, Yu Y, Hoffmann HH, Schneider WM, Razooky BS, Fernandez-Martinez J, Schmidt F, Weisblum Y, Trüeb BS, Berenguer Veiga I, Schmied K, Ebert N, Michailidis E, Peace A, Sánchez-Rivera FJ, Lowe SW, Rout MP, Hatziioannou T, Bieniasz PD, Poirier JT, MacDonald MR, Thiel V, Rice CM. Ricardo-Lax I, et al. Among authors: weisblum y. Science. 2021 Nov 26;374(6571):1099-1106. doi: 10.1126/science.abj8430. Epub 2021 Oct 14. Science. 2021. PMID: 34648371 Free PMC article.
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.
Schmidt F, Weisblum Y, Muecksch F, Hoffmann HH, Michailidis E, Lorenzi JCC, Mendoza P, Rutkowska M, Bednarski E, Gaebler C, Agudelo M, Cho A, Wang Z, Gazumyan A, Cipolla M, Caskey M, Robbiani DF, Nussenzweig MC, Rice CM, Hatziioannou T, Bieniasz PD. Schmidt F, et al. Among authors: weisblum y. J Exp Med. 2020 Nov 2;217(11):e20201181. doi: 10.1084/jem.20201181. J Exp Med. 2020. PMID: 32692348 Free PMC article.
Convergent antibody responses to SARS-CoV-2 in convalescent individuals.
Robbiani DF, Gaebler C, Muecksch F, Lorenzi JCC, Wang Z, Cho A, Agudelo M, Barnes CO, Gazumyan A, Finkin S, Hägglöf T, Oliveira TY, Viant C, Hurley A, Hoffmann HH, Millard KG, Kost RG, Cipolla M, Gordon K, Bianchini F, Chen ST, Ramos V, Patel R, Dizon J, Shimeliovich I, Mendoza P, Hartweger H, Nogueira L, Pack M, Horowitz J, Schmidt F, Weisblum Y, Michailidis E, Ashbrook AW, Waltari E, Pak JE, Huey-Tubman KE, Koranda N, Hoffman PR, West AP Jr, Rice CM, Hatziioannou T, Bjorkman PJ, Bieniasz PD, Caskey M, Nussenzweig MC. Robbiani DF, et al. Among authors: weisblum y. Nature. 2020 Aug;584(7821):437-442. doi: 10.1038/s41586-020-2456-9. Epub 2020 Jun 18. Nature. 2020. PMID: 32555388 Free PMC article.
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.
Schmidt F, Weisblum Y, Muecksch F, Hoffmann HH, Michailidis E, Lorenzi JCC, Mendoza P, Rutkowska M, Bednarski E, Gaebler C, Agudelo M, Cho A, Wang Z, Gazumyan A, Cipolla M, Caskey M, Robbiani DF, Nussenzweig MC, Rice CM, Hatziioannou T, Bieniasz PD. Schmidt F, et al. Among authors: weisblum y. bioRxiv [Preprint]. 2020 Jun 9:2020.06.08.140871. doi: 10.1101/2020.06.08.140871. bioRxiv. 2020. PMID: 32577658 Free PMC article. Updated. Preprint.
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.
Weisblum Y, Schmidt F, Zhang F, DaSilva J, Poston D, Lorenzi JC, Muecksch F, Rutkowska M, Hoffmann HH, Michailidis E, Gaebler C, Agudelo M, Cho A, Wang Z, Gazumyan A, Cipolla M, Luchsinger L, Hillyer CD, Caskey M, Robbiani DF, Rice CM, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Weisblum Y, et al. Elife. 2020 Oct 28;9:e61312. doi: 10.7554/eLife.61312. Elife. 2020. PMID: 33112236 Free PMC article.
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.
Mast FD, Fridy PC, Ketaren NE, Wang J, Jacobs EY, Olivier JP, Sanyal T, Molloy KR, Schmidt F, Rutkowska M, Weisblum Y, Rich LM, Vanderwall ER, Dambrauskas N, Vigdorovich V, Keegan S, Jiler JB, Stein ME, Olinares PDB, Herlands L, Hatziioannou T, Sather DN, Debley JS, Fenyö D, Sali A, Bieniasz PD, Aitchison JD, Chait BT, Rout MP. Mast FD, et al. Among authors: weisblum y. Elife. 2021 Dec 7;10:e73027. doi: 10.7554/eLife.73027. Elife. 2021. PMID: 34874007 Free PMC article.
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies.
Greaney AJ, Starr TN, Barnes CO, Weisblum Y, Schmidt F, Caskey M, Gaebler C, Cho A, Agudelo M, Finkin S, Wang Z, Poston D, Muecksch F, Hatziioannou T, Bieniasz PD, Robbiani DF, Nussenzweig MC, Bjorkman PJ, Bloom JD. Greaney AJ, et al. Among authors: weisblum y. Nat Commun. 2021 Jul 7;12(1):4196. doi: 10.1038/s41467-021-24435-8. Nat Commun. 2021. PMID: 34234131 Free PMC article.
High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape.
Schmidt F, Weisblum Y, Rutkowska M, Poston D, DaSilva J, Zhang F, Bednarski E, Cho A, Schaefer-Babajew DJ, Gaebler C, Caskey M, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Schmidt F, et al. Among authors: weisblum y. Nature. 2021 Dec;600(7889):512-516. doi: 10.1038/s41586-021-04005-0. Epub 2021 Sep 20. Nature. 2021. PMID: 34544114 Free PMC article.
Plasma Neutralization of the SARS-CoV-2 Omicron Variant.
Schmidt F, Muecksch F, Weisblum Y, Da Silva J, Bednarski E, Cho A, Wang Z, Gaebler C, Caskey M, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Schmidt F, et al. Among authors: weisblum y. N Engl J Med. 2022 Feb 10;386(6):599-601. doi: 10.1056/NEJMc2119641. Epub 2021 Dec 30. N Engl J Med. 2022. PMID: 35030645 Free PMC article. No abstract available.
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Barnes CO, West AP Jr, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR, Koranda N, Gristick HB, Gaebler C, Muecksch F, Lorenzi JCC, Finkin S, Hägglöf T, Hurley A, Millard KG, Weisblum Y, Schmidt F, Hatziioannou T, Bieniasz PD, Caskey M, Robbiani DF, Nussenzweig MC, Bjorkman PJ. Barnes CO, et al. Among authors: weisblum y. Cell. 2020 Aug 20;182(4):828-842.e16. doi: 10.1016/j.cell.2020.06.025. Epub 2020 Jun 24. Cell. 2020. PMID: 32645326 Free PMC article.
48 results