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Precise genomic deletions using paired prime editing.
Nat Biotechnol. 2022 Feb;40(2):218-226. doi: 10.1038/s41587-021-01025-z. Epub 2021 Oct 14.
Nat Biotechnol. 2022.
PMID: 34650269
Free PMC article.
Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma.
Alexander J, LaPlant QC, Pattwell SS, Szulzewsky F, Cimino PJ, Caruso FP, Pugliese P, Chen Z, Chardon F, Hill AJ, Spurrell C, Ahrendsen D, Pietras A, Starita LM, Hambardzumyan D, Iavarone A, Shendure J, Holland EC.
Alexander J, et al.
Glia. 2020 Dec;68(12):2486-2502. doi: 10.1002/glia.23866. Epub 2020 Jul 4.
Glia. 2020.
PMID: 32621641
Free PMC article.
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A time-resolved, multi-symbol molecular recorder via sequential genome editing.
Choi J, Chen W, Minkina A, Chardon FM, Suiter CC, Regalado SG, Domcke S, Hamazaki N, Lee C, Martin B, Daza RM, Shendure J.
Choi J, et al. Among authors: chardon fm.
Nature. 2022 Aug;608(7921):98-107. doi: 10.1038/s41586-022-04922-8. Epub 2022 Jul 6.
Nature. 2022.
PMID: 35794474
Free PMC article.
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Chromatin context-dependent regulation and epigenetic manipulation of prime editing.
Li X, Chen W, Martin BK, Calderon D, Lee C, Choi J, Chardon FM, McDiarmid T, Kim H, Lalanne JB, Nathans JF, Shendure J.
Li X, et al. Among authors: chardon fm.
bioRxiv [Preprint]. 2023 Apr 12:2023.04.12.536587. doi: 10.1101/2023.04.12.536587.
bioRxiv. 2023.
PMID: 37090511
Free PMC article.
Updated.
Preprint.
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High-content CRISPR screening.
Bock C, Datlinger P, Chardon F, Coelho MA, Dong MB, Lawson KA, Lu T, Maroc L, Norman TM, Song B, Stanley G, Chen S, Garnett M, Li W, Moffat J, Qi LS, Shapiro RS, Shendure J, Weissman JS, Zhuang X.
Bock C, et al.
Nat Rev Methods Primers. 2022;2(1):9. doi: 10.1038/s43586-022-00098-7. Epub 2022 Feb 10.
Nat Rev Methods Primers. 2022.
PMID: 37214176
Free PMC article.
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Chromatin context-dependent regulation and epigenetic manipulation of prime editing.
Li X, Chen W, Martin BK, Calderon D, Lee C, Choi J, Chardon FM, McDiarmid TA, Daza RM, Kim H, Lalanne JB, Nathans JF, Lee DS, Shendure J.
Li X, et al. Among authors: chardon fm.
Cell. 2024 May 9;187(10):2411-2427.e25. doi: 10.1016/j.cell.2024.03.020. Epub 2024 Apr 11.
Cell. 2024.
PMID: 38608704
Free article.
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Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements.
Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin B, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J.
Chardon FM, et al.
bioRxiv [Preprint]. 2024 Apr 30:2023.03.28.534017. doi: 10.1101/2023.03.28.534017.
bioRxiv. 2024.
PMID: 37034704
Free PMC article.
Preprint.
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