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Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
Li T, Cai H, Zhao Y, Li Y, Lai Y, Yao H, Liu LD, Sun Z, van Vlissingen MF, Kuiken T, GeurtsvanKessel CH, Zhang N, Zhou B, Lu L, Gong Y, Qin W, Mondal M, Duan B, Xu S, Richard AS, Raoul H, Chen J, Xu C, Wu L, Zhou H, Huang Z, Zhang X, Li J, Wang Y, Bi Y, Rockx B, Chen J, Meng FL, Lavillette D, Li D. Li T, et al. Among authors: lu l. EMBO Mol Med. 2021 Dec 7;13(12):e14544. doi: 10.15252/emmm.202114544. Epub 2021 Nov 17. EMBO Mol Med. 2021. PMID: 34672091 Free PMC article.
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion.
Xia S, Liu M, Wang C, Xu W, Lan Q, Feng S, Qi F, Bao L, Du L, Liu S, Qin C, Sun F, Shi Z, Zhu Y, Jiang S, Lu L. Xia S, et al. Among authors: lu l. Cell Res. 2020 Apr;30(4):343-355. doi: 10.1038/s41422-020-0305-x. Epub 2020 Mar 30. Cell Res. 2020. PMID: 32231345 Free PMC article.
Identification of Human Single-Domain Antibodies against SARS-CoV-2.
Wu Y, Li C, Xia S, Tian X, Kong Y, Wang Z, Gu C, Zhang R, Tu C, Xie Y, Yang Z, Lu L, Jiang S, Ying T. Wu Y, et al. Among authors: lu l. Cell Host Microbe. 2020 Jun 10;27(6):891-898.e5. doi: 10.1016/j.chom.2020.04.023. Epub 2020 May 14. Cell Host Microbe. 2020. PMID: 32413276 Free PMC article.
Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD.
Zhou Y, Liu Z, Li S, Xu W, Zhang Q, Silva IT, Li C, Wu Y, Jiang Q, Liu Z, Wang Q, Guo Y, Wu J, Gu C, Cai X, Qu D, Mayer CT, Wang X, Jiang S, Ying T, Yuan Z, Xie Y, Wen Y, Lu L, Wang Q. Zhou Y, et al. Among authors: lu l. Cell Rep. 2021 Feb 2;34(5):108699. doi: 10.1016/j.celrep.2021.108699. Epub 2021 Jan 12. Cell Rep. 2021. PMID: 33485405 Free PMC article.
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