Greninger AL - Search Results

1

Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets.

Cox RM, Wolf JD, Lieber CM, Sourimant J, Lin MJ, Babusis D, DuPont V, Chan J, Barrett KT, Lye D, Kalla R, Chun K, Mackman RL, Ye C, Cihlar T, Martinez-Sobrido L, Greninger AL, Bilello JP, Plemper RK. Cox RM, et al. Among authors: greninger al. Nat Commun. 2021 Nov 5;12(1):6415. doi: 10.1038/s41467-021-26760-4. Nat Commun. 2021. PMID: 34741049 Free PMC article.

2

The Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity.

Thakkar VD, Cox RM, Sawatsky B, da Fontoura Budaszewski R, Sourimant J, Wabbel K, Makhsous N, Greninger AL, von Messling V, Plemper RK. Thakkar VD, et al. Among authors: greninger al. J Virol. 2018 Mar 28;92(8):e02064-17. doi: 10.1128/JVI.02064-17. Print 2018 Apr 15. J Virol. 2018. PMID: 29437959 Free PMC article.

3

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses.

Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Luczo JM, Ganti K, Cox RM, Sticher ZM, Edpuganti V, Mitchell DG, Lockwood MA, Kolykhalov AA, Greninger AL, Moore ML, Painter GR, Lowen AC, Tompkins SM, Fearns R, Natchus MG, Plemper RK. Yoon JJ, et al. Among authors: greninger al. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00766-18. doi: 10.1128/AAC.00766-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29891600 Free PMC article.

4

VAPiD: a lightweight cross-platform viral annotation pipeline and identification tool to facilitate virus genome submissions to NCBI GenBank.

Shean RC, Makhsous N, Stoddard GD, Lin MJ, Greninger AL. Shean RC, et al. Among authors: greninger al. BMC Bioinformatics. 2019 Jan 23;20(1):48. doi: 10.1186/s12859-019-2606-y. BMC Bioinformatics. 2019. PMID: 30674273 Free PMC article.

5

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.

Toots M, Yoon JJ, Cox RM, Hart M, Sticher ZM, Makhsous N, Plesker R, Barrena AH, Reddy PG, Mitchell DG, Shean RC, Bluemling GR, Kolykhalov AA, Greninger AL, Natchus MG, Painter GR, Plemper RK. Toots M, et al. Among authors: greninger al. Sci Transl Med. 2019 Oct 23;11(515):eaax5866. doi: 10.1126/scitranslmed.aax5866. Sci Transl Med. 2019. PMID: 31645453 Free PMC article.

6

Comparative genomics and full-length Tprk profiling of Treponema pallidum subsp. pallidum reinfection.

Addetia A, Tantalo LC, Lin MJ, Xie H, Huang ML, Marra CM, Greninger AL. Addetia A, et al. Among authors: greninger al. PLoS Negl Trop Dis. 2020 Apr 6;14(4):e0007921. doi: 10.1371/journal.pntd.0007921. eCollection 2020 Apr. PLoS Negl Trop Dis. 2020. PMID: 32251462 Free PMC article.

7

Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.

Cox RM, Sourimant J, Toots M, Yoon JJ, Ikegame S, Govindarajan M, Watkinson RE, Thibault P, Makhsous N, Lin MJ, Marengo JR, Sticher Z, Kolykhalov AA, Natchus MG, Greninger AL, Lee B, Plemper RK. Cox RM, et al. Among authors: greninger al. Nat Microbiol. 2020 Oct;5(10):1232-1246. doi: 10.1038/s41564-020-0752-7. Epub 2020 Jul 13. Nat Microbiol. 2020. PMID: 32661315 Free PMC article.

8

Sensitive Recovery of Complete SARS-CoV-2 Genomes from Clinical Samples by Use of Swift Biosciences' SARS-CoV-2 Multiplex Amplicon Sequencing Panel.

Addetia A, Lin MJ, Peddu V, Roychoudhury P, Jerome KR, Greninger AL. Addetia A, et al. Among authors: greninger al. J Clin Microbiol. 2020 Dec 17;59(1):e02226-20. doi: 10.1128/JCM.02226-20. Print 2020 Dec 17. J Clin Microbiol. 2020. PMID: 33046529 Free PMC article. No abstract available.

9

Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain.

Outlaw VK, Bovier FT, Mears MC, Cajimat MN, Zhu Y, Lin MJ, Addetia A, Lieberman NAP, Peddu V, Xie X, Shi PY, Greninger AL, Gellman SH, Bente DA, Moscona A, Porotto M. Outlaw VK, et al. Among authors: greninger al. mBio. 2020 Oct 20;11(5):e01935-20. doi: 10.1128/mBio.01935-20. mBio. 2020. PMID: 33082259 Free PMC article.

10

In Vivo Generation of BK and JC Polyomavirus Defective Viral Genomes in Human Urine Samples Associated with Higher Viral Loads.

Addetia A, Phung Q, Bradley BT, Lin MJ, Zhu H, Xie H, Huang ML, Greninger AL. Addetia A, et al. Among authors: greninger al. J Virol. 2021 May 24;95(12):e00250-21. doi: 10.1128/JVI.00250-21. Print 2021 May 24. J Virol. 2021. PMID: 33827948 Free PMC article.

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