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Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike.
Changrob S, Fu Y, Guthmiller JJ, Halfmann PJ, Li L, Stamper CT, Dugan HL, Accola M, Rehrauer W, Zheng NY, Huang M, Wang J, Erickson SA, Utset HA, Graves HM, Amanat F, Sather DN, Krammer F, Kawaoka Y, Wilson PC. Changrob S, et al. Among authors: dugan hl. mBio. 2021 Dec 21;12(6):e0297521. doi: 10.1128/mBio.02975-21. Epub 2021 Nov 16. mBio. 2021. PMID: 34781736 Free PMC article. Clinical Trial.
Antigen-specific memory NK cell responses against HIV and influenza use the NKG2/HLA-E axis.
Jost S, Lucar O, Lee E, Yoder T, Kroll K, Sugawara S, Smith S, Jones R, Tweet G, Werner A, Tomezsko PJ, Dugan HL, Ghofrani J, Rascle P, Altfeld M, Müller-Trutwin M, Goepfert P, Reeves RK. Jost S, et al. Among authors: dugan hl. Sci Immunol. 2023 Dec 8;8(90):eadi3974. doi: 10.1126/sciimmunol.adi3974. Epub 2023 Dec 8. Sci Immunol. 2023. PMID: 38064568 Free PMC article.
Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial.
Bernstein DI, Guptill J, Naficy A, Nachbagauer R, Berlanda-Scorza F, Feser J, Wilson PC, Solórzano A, Van der Wielen M, Walter EB, Albrecht RA, Buschle KN, Chen YQ, Claeys C, Dickey M, Dugan HL, Ermler ME, Freeman D, Gao M, Gast C, Guthmiller JJ, Hai R, Henry C, Lan LY, McNeal M, Palm AE, Shaw DG, Stamper CT, Sun W, Sutton V, Tepora ME, Wahid R, Wenzel H, Wohlbold TJ, Innis BL, García-Sastre A, Palese P, Krammer F. Bernstein DI, et al. Among authors: dugan hl. Lancet Infect Dis. 2020 Jan;20(1):80-91. doi: 10.1016/S1473-3099(19)30393-7. Epub 2019 Oct 17. Lancet Infect Dis. 2020. PMID: 31630990 Free PMC article. Clinical Trial.
Aging and influenza vaccine-induced immunity.
Dugan HL, Henry C, Wilson PC. Dugan HL, et al. Cell Immunol. 2020 Feb;348:103998. doi: 10.1016/j.cellimm.2019.103998. Epub 2019 Oct 31. Cell Immunol. 2020. PMID: 31733824 Review.
Proinflammatory IgG Fc structures in patients with severe COVID-19.
Chakraborty S, Gonzalez J, Edwards K, Mallajosyula V, Buzzanco AS, Sherwood R, Buffone C, Kathale N, Providenza S, Xie MM, Andrews JR, Blish CA, Singh U, Dugan H, Wilson PC, Pham TD, Boyd SD, Nadeau KC, Pinsky BA, Zhang S, Memoli MJ, Taubenberger JK, Morales T, Schapiro JM, Tan GS, Jagannathan P, Wang TT. Chakraborty S, et al. medRxiv [Preprint]. 2020 Nov 10:2020.05.15.20103341. doi: 10.1101/2020.05.15.20103341. medRxiv. 2020. PMID: 32511463 Free PMC article. Updated. Preprint.
SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike.
Guthmiller JJ, Stovicek O, Wang J, Changrob S, Li L, Halfmann P, Zheng NY, Utset H, Stamper CT, Dugan HL, Miller WD, Huang M, Dai YN, Nelson CA, Hall PD, Jansen M, Shanmugarajah K, Donington JS, Krammer F, Fremont DH, Joachimiak A, Kawaoka Y, Tesic V, Madariaga ML, Wilson PC. Guthmiller JJ, et al. Among authors: dugan hl. bioRxiv [Preprint]. 2020 Sep 13:2020.09.12.294066. doi: 10.1101/2020.09.12.294066. bioRxiv. 2020. PMID: 32935099 Free PMC article. Updated. Preprint.
Distinct B cell subsets give rise to antigen-specific antibody responses against SARS-CoV-2.
Stamper CT, Dugan HL, Li L, Asby NW, Halfmann PJ, Guthmiller JJ, Zheng NY, Huang M, Stovicek O, Wang J, Madariaga ML, Shanmugarajah K, Jansen MO, Amanat F, Stewart I, Changrob S, Utset HA, Huang J, Nelson CA, Dai YN, Hall PD, Jedrzejczak RP, Joachimiak A, Krammer F, Fremont DH, Kawaoka Y, Wilson PC. Stamper CT, et al. Among authors: dugan hl. Res Sq [Preprint]. 2020 Sep 25:rs.3.rs-80476. doi: 10.21203/rs.3.rs-80476/v1. Res Sq. 2020. PMID: 32995763 Free PMC article. Preprint.
Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial.
Madariaga MLL, Guthmiller JJ, Schrantz S, Jansen MO, Christensen C, Kumar M, Prochaska M, Wool G, Durkin-Celauro A, Oh WH, Trockman L, Vigneswaran J, Keskey R, Shaw DG, Dugan H, Zheng NY, Cobb M, Utset H, Wang J, Stovicek O, Bethel C, Matushek S, Giurcanu M, Beavis KG, di Sabato D, Meltzer D, Ferguson MK, Kress JP, Shanmugarajah K, Matthews JB, Fung JF, Wilson PC, Alverdy JC, Donington JS. Madariaga MLL, et al. J Intern Med. 2021 Apr;289(4):559-573. doi: 10.1111/joim.13185. Epub 2020 Nov 3. J Intern Med. 2021. PMID: 33034095 Free PMC article.
Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses.
Guthmiller JJ, Lan LY, Fernández-Quintero ML, Han J, Utset HA, Bitar DJ, Hamel NJ, Stovicek O, Li L, Tepora M, Henry C, Neu KE, Dugan HL, Borowska MT, Chen YQ, Liu STH, Stamper CT, Zheng NY, Huang M, Palm AE, García-Sastre A, Nachbagauer R, Palese P, Coughlan L, Krammer F, Ward AB, Liedl KR, Wilson PC. Guthmiller JJ, et al. Among authors: dugan hl. Immunity. 2020 Dec 15;53(6):1230-1244.e5. doi: 10.1016/j.immuni.2020.10.005. Epub 2020 Oct 22. Immunity. 2020. PMID: 33096040 Free PMC article.
31 results