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PARP Inhibitors - Trapped in a Toxic Love Affair.
Krastev DB, Wicks AJ, Lord CJ. Krastev DB, et al. Among authors: lord cj. Cancer Res. 2021 Nov 15;81(22):5605-5607. doi: 10.1158/0008-5472.CAN-21-3201. Cancer Res. 2021. PMID: 34782321
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: lord cj. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
DNA repair deficiency as a therapeutic target in cancer.
Martin SA, Lord CJ, Ashworth A. Martin SA, et al. Among authors: lord cj. Curr Opin Genet Dev. 2008 Feb;18(1):80-6. doi: 10.1016/j.gde.2008.01.016. Epub 2008 Mar 14. Curr Opin Genet Dev. 2008. PMID: 18343102 Review.
Bringing DNA repair in tumors into focus.
Lord CJ, Ashworth A. Lord CJ, et al. Clin Cancer Res. 2009 May 15;15(10):3241-3. doi: 10.1158/1078-0432.CCR-09-0434. Epub 2009 May 15. Clin Cancer Res. 2009. PMID: 19447863
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.
Mendes-Pereira AM, Martin SA, Brough R, McCarthy A, Taylor JR, Kim JS, Waldman T, Lord CJ, Ashworth A. Mendes-Pereira AM, et al. Among authors: lord cj. EMBO Mol Med. 2009 Sep;1(6-7):315-22. doi: 10.1002/emmm.200900041. EMBO Mol Med. 2009. PMID: 20049735 Free PMC article.
250 results