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266 results

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Efficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock-A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study).
Bauer M, Weyland A, Marx G, Bloos F, Weber S, Weiler N, Kluge S, Diers A, Simon TP, Lautenschläger I, Gründling M, Jaschinski U, Simon P, Nierhaus A, Moerer O, Reill L, Jörres A, Guo R, Loeffler M, Reinhart K, Riedemann N. Bauer M, et al. Among authors: weiler n. Crit Care Explor. 2021 Nov 17;3(11):e0577. doi: 10.1097/CCE.0000000000000577. eCollection 2021 Nov. Crit Care Explor. 2021. PMID: 34806021 Free PMC article.
Epidemiology of sepsis in Germany: results from a national prospective multicenter study.
Engel C, Brunkhorst FM, Bone HG, Brunkhorst R, Gerlach H, Grond S, Gruendling M, Huhle G, Jaschinski U, John S, Mayer K, Oppert M, Olthoff D, Quintel M, Ragaller M, Rossaint R, Stuber F, Weiler N, Welte T, Bogatsch H, Hartog C, Loeffler M, Reinhart K. Engel C, et al. Among authors: weiler n. Intensive Care Med. 2007 Apr;33(4):606-18. doi: 10.1007/s00134-006-0517-7. Epub 2007 Feb 24. Intensive Care Med. 2007. PMID: 17323051 Clinical Trial.
Intensive insulin therapy and pentastarch resuscitation in severe sepsis.
Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, Moerer O, Gruendling M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffler M, Reinhart K; German Competence Network Sepsis (SepNet). Brunkhorst FM, et al. Among authors: weiler n. N Engl J Med. 2008 Jan 10;358(2):125-39. doi: 10.1056/NEJMoa070716. N Engl J Med. 2008. PMID: 18184958 Free article. Clinical Trial.
The German quality indicators in intensive care medicine 2013--second edition.
Braun JP, Kumpf O, Deja M, Brinkmann A, Marx G, Bloos F, Kaltwasser A, Dubb R, Muhl E, Greim C, Bause H, Weiler N, Chop I, Waydhas C, Spies C. Braun JP, et al. Among authors: weiler n. Ger Med Sci. 2013 Jul 16;11:Doc09. doi: 10.3205/000177. Print 2013. Ger Med Sci. 2013. PMID: 23904823 Free PMC article.
Voluntary peer review as innovative tool for quality improvement in the intensive care unit--a retrospective descriptive cohort study in German intensive care units.
Kumpf O, Bloos F, Bause H, Brinkmann A, Deja M, Marx G, Kaltwasser A, Dubb R, Muhl E, Greim CA, Weiler N, Chop I, Jonitz G, Schaefer H, Felsenstein M, Liebeskind U, Leffmann C, Jungbluth A, Waydhas C, Pronovost P, Spies C, Braun JP; NeQuI-Group (Netzwerk Qualität in der Intensivmedizin). Kumpf O, et al. Among authors: weiler n. Ger Med Sci. 2014 Dec 15;12:Doc17. doi: 10.3205/000202. eCollection 2014. Ger Med Sci. 2014. PMID: 25587245 Free PMC article.
Hydroxyethyl starch (HES 130/0.4) impairs intestinal barrier integrity and metabolic function: findings from a mouse model of the isolated perfused small intestine.
Wong YL, Lautenschläger I, Dombrowsky H, Zitta K, Bein B, Krause T, Goldmann T, Frerichs I, Steinfath M, Weiler N, Albrecht M. Wong YL, et al. Among authors: weiler n. PLoS One. 2015 Mar 23;10(3):e0121497. doi: 10.1371/journal.pone.0121497. eCollection 2015. PLoS One. 2015. PMID: 25799493 Free PMC article.
Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial.
Keh D, Trips E, Marx G, Wirtz SP, Abduljawwad E, Bercker S, Bogatsch H, Briegel J, Engel C, Gerlach H, Goldmann A, Kuhn SO, Hüter L, Meier-Hellmann A, Nierhaus A, Kluge S, Lehmke J, Loeffler M, Oppert M, Resener K, Schädler D, Schuerholz T, Simon P, Weiler N, Weyland A, Reinhart K, Brunkhorst FM; SepNet–Critical Care Trials Group. Keh D, et al. Among authors: weiler n. JAMA. 2016 Nov 1;316(17):1775-1785. doi: 10.1001/jama.2016.14799. JAMA. 2016. PMID: 27695824 Clinical Trial.
Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial.
Bloos F, Rüddel H, Thomas-Rüddel D, Schwarzkopf D, Pausch C, Harbarth S, Schreiber T, Gründling M, Marshall J, Simon P, Levy MM, Weiss M, Weyland A, Gerlach H, Schürholz T, Engel C, Matthäus-Krämer C, Scheer C, Bach F, Riessen R, Poidinger B, Dey K, Weiler N, Meier-Hellmann A, Häberle HH, Wöbker G, Kaisers UX, Reinhart K; MEDUSA study group. Bloos F, et al. Among authors: weiler n. Intensive Care Med. 2017 Nov;43(11):1602-1612. doi: 10.1007/s00134-017-4782-4. Epub 2017 May 2. Intensive Care Med. 2017. PMID: 28466151 Clinical Trial.
The effect of a novel extracorporeal cytokine hemoadsorption device on IL-6 elimination in septic patients: A randomized controlled trial.
Schädler D, Pausch C, Heise D, Meier-Hellmann A, Brederlau J, Weiler N, Marx G, Putensen C, Spies C, Jörres A, Quintel M, Engel C, Kellum JA, Kuhlmann MK. Schädler D, et al. Among authors: weiler n. PLoS One. 2017 Oct 30;12(10):e0187015. doi: 10.1371/journal.pone.0187015. eCollection 2017. PLoS One. 2017. PMID: 29084247 Free PMC article. Clinical Trial.
266 results